PDB entry 3fgu

View 3fgu on RCSB PDB site
Description: Catalytic complex of Human Glucokinase
Class: transferase
Keywords: Glucokinase, Hexokinase IV, ATP-binding, Diabetes mellitus, Disease mutation, Glycolysis, Kinase, Nucleotide-binding, Transferase
Deposited on 2008-12-08, released 2009-12-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35557 (16-End)
      • expression tag (9-15)
    Domains in SCOPe 2.08: d3fgua1, d3fgua2, d3fgua3
  • Heterogens: BGC, ANP, MG, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fguA (A:)
mghhhhhhenlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasv
kmlptyvrstpegsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedam
tgtaemlfdyisecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasg
aegnnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacym
eemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekligg
kymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstl
glrpsttdcdivrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvykl
hpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3fguA (A:)
nlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrs
tpsevgdflsldlggtnfrvmlvkvgegqwsvktkhqmysipedamtgtaemlfdyisec
isdfldkhqmkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaikr
rgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegrm
cvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlvd
enllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrrac
esvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrlt
psceitfieseegsgrgaalvsavack