PDB entry 3fgs

View 3fgs on RCSB PDB site
Description: Crystal structure of G65R/K206E double mutant of the N-lobe human transferrin
Class: metal transport
Keywords: Human transferrin, Iron binding protein, Dilysine pair, Disease mutation, Glycoprotein, Ion transport, Iron, Iron transport, Metal-binding, Methylation, Phosphoprotein, Polymorphism, Secreted, Transport, METAL TRANSPORT
Deposited on 2008-12-08, released 2009-05-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serotransferrin
    Species: Homo sapiens [TaxId:9606]
    Gene: PRO1400, TF, transferrin
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02787
      • engineered (64)
      • engineered (205)
    Domains in SCOPe 2.07: d3fgsa_
  • Heterogens: CO3, FE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fgsA (A:)
vpdktvrwcavseheatkcqsfrdhmksvipsdgpsvacvkkasyldciraiaaneadav
tldarlvydaylapnnlkpvvaefygskedpqtfyyavavvkkdsgfqmnqlrgkkscht
glgrsagwnipigllycdlpeprkplekavanffsgscapcadgtdfpqlcqlcpgcgcs
tlnqyfgysgafkclkdgagdvafvehstifenlankadrdqyellcldntrkpvdeykd
chlaqvpshtvvarsmggkedliwellnqaqehfgkdkskefqlfssphgkdllfkdsah
gflkvpprmdakmylgyeyvtairnlregtcpeaptd

    Sequence, based on observed residues (ATOM records): (download) 
    >3fgsA (A:)
dktvrwcavseheatkcqsfrdhmksvipsdgpsvacvkkasyldciraiaaneadavtl
darlvydaylapnnlkpvvaefygskedpqtfyyavavvkkdsgfqmnqlrgkkschtgl
grsagwnipigllycdlpeprkplekavanffsgscapcadgtdfpqlcqlcpgcgcstl
nqyfgysgafkclkdgagdvafvehstifenlankadrdqyellcldntrkpvdeykdch
laqvpshtvvarsmggkedliwellnqaqehfgkdkskefqlfssphgkdllfkdsahgf
lkvpprmdakmylgyeyvtairnlregtc