PDB entry 3ff7

View 3ff7 on RCSB PDB site
Description: Structure of NK cell receptor KLRG1 bound to E-cadherin
Class: Cell adhesion/Immune system
Keywords: KLRG1-cadherin complex, Calcium, Cell adhesion, Cell junction, Cell membrane, Cleavage on pair of basic residues, Disease mutation, Glycoprotein, Membrane, Phosphoprotein, Polymorphism, Transmembrane, Alternative splicing, Lectin, Receptor, Signal-anchor, Cell adhesion-Immune system COMPLEX
Deposited on 2008-12-02, released 2009-07-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: epithelial cadherin
    Species: Homo sapiens [TaxId:9606]
    Gene: CDH1, CDHE, UVO
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12830 (1-99)
      • expression tag (0)
      • engineered (9)
    Domains in SCOPe 2.08: d3ff7a1, d3ff7a2
  • Chain 'B':
    Compound: epithelial cadherin
    Species: Homo sapiens [TaxId:9606]
    Gene: CDH1, CDHE, UVO
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12830 (1-99)
      • expression tag (0)
      • engineered (9)
    Domains in SCOPe 2.08: d3ff7b1, d3ff7b2
  • Chain 'C':
    Compound: Killer cell lectin-like receptor subfamily G member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KLRG1, CLEC15A, MAFA, MAFAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96E93 (0-111)
      • engineered (56)
    Domains in SCOPe 2.08: d3ff7c_
  • Chain 'D':
    Compound: Killer cell lectin-like receptor subfamily G member 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KLRG1, CLEC15A, MAFA, MAFAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96E93 (0-111)
      • engineered (56)
    Domains in SCOPe 2.08: d3ff7d_
  • Heterogens: ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ff7A (A:)
mdwvippislpenekgpfpknlvqiksnkdkegkvfysitgqgadtppvgvfiieretgw
lkvtepldreriatytlfshavssngnavedpmeilitvt

    Sequence, based on observed residues (ATOM records): (download) 
    >3ff7A (A:)
mdwvippislpkgpfpknlvqiksnkdkegkvfysitgqgadtppvgvfiieretgwlkv
tepldreriatytlfshavssngnavedpmeilitvt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ff7B (B:)
mdwvippislpenekgpfpknlvqiksnkdkegkvfysitgqgadtppvgvfiieretgw
lkvtepldreriatytlfshavssngnavedpmeilitvt

    Sequence, based on observed residues (ATOM records): (download) 
    >3ff7B (B:)
mdwvippislpengpfpknlvqiksnkdkegkvfysitgqgadtppvgvfiieretgwlk
vtepldreriatytlfshavssngnavedpmeilitvt

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3ff7C (C:)
cpdrwmkygnhcyyfsveekdwnsslefclardshllvitdnqemsllqvflseafswig
lrnnsgwrwedgsplnfsrissnsfvqtcgainknglqasscevplhwvckk

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3ff7D (D:)
cpdrwmkygnhcyyfsveekdwnsslefclardshllvitdnqemsllqvflseafswig
lrnnsgwrwedgsplnfsrissnsfvqtcgainknglqasscevplhwvckk