PDB entry 3ff6

View 3ff6 on RCSB PDB site
Description: Human ACC2 CT domain with CP-640186
Class: ligase
Keywords: Acetyl CoA Carboxylase, ACC2, ACC, metabolic disorder, fatty acid metabolism, ATP-binding, Biotin, Fatty acid biosynthesis, Ligase, Lipid synthesis, Manganese, Membrane, Metal-binding, Multifunctional enzyme, Nucleotide-binding, Phosphoprotein
Deposited on 2008-12-02, released 2009-05-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 3.19 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA carboxylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACACB, ACC2, ACCB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ff6a1, d3ff6a2
  • Chain 'B':
    Compound: Acetyl-CoA carboxylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACACB, ACC2, ACCB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ff6b1, d3ff6b2
  • Chain 'C':
    Compound: Acetyl-CoA carboxylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACACB, ACC2, ACCB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ff6c1, d3ff6c2
  • Chain 'D':
    Compound: Acetyl-CoA carboxylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACACB, ACC2, ACCB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ff6d1, d3ff6d2
  • Heterogens: RCP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ff6A (A:)
gntpyvtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvld
sqgqlvemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllyl
rasemaraegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytr
isslnsvhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislv
tcraigigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngv
shitvpddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlag
rphptlkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpad
panldseakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqv
lkfgayivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlep
egtveikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyh
qvavqfadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgels
hvhiqsmlrrwfvetegavkaylwdnnqvvvqwleqhwqagdgprstirenitylkhdsv
lktirglveenpevavdcviylsqhispaeraqvvhllse

    Sequence, based on observed residues (ATOM records): (download) 
    >3ff6A (A:)
pyvtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvldsqg
qlvemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllylras
emaraegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytriss
lnsvhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislvtcr
aigigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngvshi
tvpddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlagrph
ptlkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpadpan
ldseakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqvlkf
gayivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlepegt
veikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyhqva
vqfadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgelshvh
iqsmlrrwfvetegavkaylwdnnqvvvqwleqhwqrstirenitylkhdsvlktirglv
eenpevavdcviylsqhispaeraqvvhll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ff6B (B:)
gntpyvtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvld
sqgqlvemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllyl
rasemaraegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytr
isslnsvhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislv
tcraigigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngv
shitvpddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlag
rphptlkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpad
panldseakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqv
lkfgayivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlep
egtveikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyh
qvavqfadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgels
hvhiqsmlrrwfvetegavkaylwdnnqvvvqwleqhwqagdgprstirenitylkhdsv
lktirglveenpevavdcviylsqhispaeraqvvhllse

    Sequence, based on observed residues (ATOM records): (download) 
    >3ff6B (B:)
vtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvldsqgql
vemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllylrasem
araegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytrissln
svhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislvtcrai
gigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngvshitv
pddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlagrphpt
lkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpadpanld
seakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqvlkfga
yivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlepegtve
ikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyhqvavq
fadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgelshvhiq
smlrrwfvetegavkaylwdnnqvvvqwleqhwqatirenitylkhdsvlktirglveen
pevavdcviylsqhispaeraqvvhlls

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3ff6C (C:)
gntpyvtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvld
sqgqlvemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllyl
rasemaraegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytr
isslnsvhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislv
tcraigigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngv
shitvpddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlag
rphptlkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpad
panldseakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqv
lkfgayivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlep
egtveikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyh
qvavqfadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgels
hvhiqsmlrrwfvetegavkaylwdnnqvvvqwleqhwqagdgprstirenitylkhdsv
lktirglveenpevavdcviylsqhispaeraqvvhllse

    Sequence, based on observed residues (ATOM records): (download) 
    >3ff6C (C:)
vtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdypkdiltytelvldsqgqlv
emnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllylrasema
raegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytrisslns
vhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislvtcraig
igaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngvshitvp
ddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlagrphptl
kgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpadpanlds
eakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqvlkfgay
ivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlepegtvei
kfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyhqvavqf
adfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgelhvhiqsm
lrrwfvetegavkaylwdnnqvvvqwleqhwqrstirenitylkhdsvlktirglveenp
evavdcviylsqhispaeraqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3ff6D (D:)
gntpyvtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvld
sqgqlvemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllyl
rasemaraegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytr
isslnsvhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislv
tcraigigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngv
shitvpddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlag
rphptlkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpad
panldseakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqv
lkfgayivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlep
egtveikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyh
qvavqfadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgels
hvhiqsmlrrwfvetegavkaylwdnnqvvvqwleqhwqagdgprstirenitylkhdsv
lktirglveenpevavdcviylsqhispaeraqvvhllse

    Sequence, based on observed residues (ATOM records): (download) 
    >3ff6D (D:)
vtkdllqakrfqaqtlgttyiydfpemfrqalfklwgspdkypkdiltytelvldsqgql
vemnrlpggnevgmvafkmrfktqeypegrdvivignditfrigsfgpgedllylrasem
araegipkiyvaansgarigmaeeikhmfhvawvdpedphkgfkylyltpqdytrissln
svhckhieeggesrymitdiigkddglgvenlrgsgmiagesslayeeivtislvtcrai
gigaylvrlgqrviqvenshiiltgasalnkvlgrevytsnnqlggvqimhyngvshitv
pddfegvytilewlsympkdnhspvpiitptdpidreieflpsrapydprwmlagrphpt
lkgtwqsgffdhgsfkeimapwaqtvvtgrarlggipvgviavetrtvevavpadpanld
seakiiqqagqvwfpdsayktaqaikdfnreklplmifanwrgfsggmkdmydqvlkfga
yivdglrqykqpiliyippyaelrggswvvidatinplciemyadkesrggvlepegtve
ikfrkkdliksmrridpaykklmeqlgepdlsdkdrkdlegrlkaredlllpiyhqvavq
fadfhdtpgrmlekgvisdilewktartflywrlrrllledqvkqeilqasgelshvhiq
smlrrwfvetegavkaylwdnnqvvvqwleqhwqarstirenitylkhdsvlktirglve
enpevavdcviyl