PDB entry 3fei

View 3fei on RCSB PDB site
Description: Design and biological evaluation of novel, balanced dual PPARa/g agonists
Class: transcription
Keywords: NUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, DIABETES, Activator, DNA-binding, Metal-binding, Nucleus, Polymorphism, Receptor, Transcription, Transcription regulation, Zinc, Zinc-finger
Deposited on 2008-11-30, released 2009-10-20
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-10-20, with a file datestamp of 2009-10-16.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.219
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARA, NR1C1, PPAR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3feia_
  • Chain 'Z':
    Compound: Peptide motif 5 of Nuclear receptor coactivator 1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CTM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3feiA (A:)
dlkslakriyeaylknfnmnkvkarvilsgkasnnppfvihdmetlcmaektlvaklvan
giqnkeaevrifhccqctsvetvteltefakaipgfanldlndqvtllkygvyeaifaml
ssvmnkdgmlvaygngfitreflkslrkpfcdimepkfdfamkfnalelddsdislfvaa
iiccgdrpgllnvghiekmqegivhvlrlhlqsnhpddiflfpkllqkmadlrqlvteha
qlvqiikktesdaalhpllqeiyrdmy

    Sequence, based on observed residues (ATOM records): (download) 
    >3feiA (A:)
dlkslakriyeaylknfnmnkvkarvilspfvihdmetlcmaekeaevrifhccqctsve
tvteltefakaipgfanldlndqvtllkygvyeaifamlssvmnkdgmlvaygngfitre
flkslrkpfcdimepkfdfamkfnalelddsdislfvaaiiccgdrpgllnvghiekmqe
givhvlrlhlqsnhpddiflfpkllqkmadlrqlvtehaqlvqiikktesdaalhpllqe
iyrdmy

  • Chain 'Z':
    No sequence available.