PDB entry 3fe3

View 3fe3 on RCSB PDB site
Description: Crystal structure of the kinase MARK3/Par-1: T211A-S215A double mutant
Class: transferase
Keywords: SERINE/THREONINE PROTEIN KINASE; MARK;PAR-1; KIN1; UBA DOMAIN;C-TAK1;P78;MARK3, ATP-binding, Kinase, Nucleotide-binding, Phosphoprotein, Serine/threonine-protein kinase, Transferase
Deposited on 2008-11-27, released 2008-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.199
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MAP/microtubule affinity-regulating kinase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27448
      • engineered (171)
      • engineered (175)
    Domains in SCOPe 2.08: d3fe3a_
  • Chain 'B':
    Compound: MAP/microtubule affinity-regulating kinase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MARK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27448
      • engineered (171)
      • engineered (175)
    Domains in SCOPe 2.08: d3fe3b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fe3A (A:)
gnsiascadeqphignyrllktigkgnfakvklarhiltgrevaikiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylimeyasggevfdylvahgrmkekearskf
rqivsavqychqkrivhrdlkaenllldadmnikiadfgfsneftvggkldafcgappya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkrflvlnpikrgtleqimkdrwinagheedelkpfvepeldisdqkridimvgmg
ysqeeiqeslskmkydeitatylllgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3fe3A (A:)
qphignyrllktigkgnfakvklarhiltgrevaikiidktqlnptslqklfrevrimki
lnhpnivklfevietektlylimeyasggevfdylvahgrmkekearskfrqivsavqyc
hqkrivhrdlkaenllldadmnikiadfgfsneftvggkldafcgappyaapelfqgkky
dgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkrflv
lnpikrgtleqimkdrwinagheedelkpfvepeldisdqkridimvgmgysqeeiqesl
skmkydeitatylllgr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fe3B (B:)
gnsiascadeqphignyrllktigkgnfakvklarhiltgrevaikiidktqlnptslqk
lfrevrimkilnhpnivklfevietektlylimeyasggevfdylvahgrmkekearskf
rqivsavqychqkrivhrdlkaenllldadmnikiadfgfsneftvggkldafcgappya
apelfqgkkydgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstd
cenllkrflvlnpikrgtleqimkdrwinagheedelkpfvepeldisdqkridimvgmg
ysqeeiqeslskmkydeitatylllgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >3fe3B (B:)
qphignyrllktigkgnfakvklarhiltgrevaikiidktqlnptslqklfrevrimki
lnhpnivklfevietektlylimeyasggevfdylvahgrmkekearskfrqivsavqyc
hqkrivhrdlkaenllldadmnikiadfgfsneftvggkldafcgappyaapelfqgkky
dgpevdvwslgvilytlvsgslpfdgqnlkelrervlrgkyripfymstdcenllkrflv
lnpikrgtleqimkdrwinagheedelkpfvepeldisdqkridimvgmgysqeeiqesl
skmkydeitatylllgr