PDB entry 3fdm

View 3fdm on RCSB PDB site
Description: alpha/beta foldamer in complex with Bcl-xL
Class: apoptosis
Keywords: protein-peptide complex, helical bundle, foldamer, apoptosis, Alternative splicing, Membrane, Mitochondrion, Nucleus, Transmembrane
Deposited on 2008-11-26, released 2009-03-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: apoptosis regulator bcl-x
    Species: Homo sapiens [TaxId:9606]
    Gene: Bcl-x
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (5-30)
      • expression tag (0-4)
    • Uniprot Q07817 (31-End)
    Domains in SCOPe 2.08: d3fdma1, d3fdma2
  • Chain 'B':
    Compound: apoptosis regulator bcl-x
    Species: Homo sapiens [TaxId:9606]
    Gene: Bcl-x
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (5-30)
      • expression tag (0-4)
    • Uniprot Q07817 (31-End)
    Domains in SCOPe 2.08: d3fdmb1, d3fdmb2
  • Chain 'C':
    Compound: apoptosis regulator bcl-x
    Species: Homo sapiens [TaxId:9606]
    Gene: Bcl-x
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3fdmc_
  • Chain 'D':
    Compound: alpha/beta-peptide foldamer
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FDM
  • Chain 'E':
    Compound: alpha/beta-peptide foldamer
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FDM
  • Chain 'F':
    Compound: alpha/beta-peptide foldamer
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 3FDM
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fdmA (A:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >3fdmA (A:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fdmB (B:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >3fdmB (B:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3fdmC (C:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >3fdmC (C:)
sqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsqlhitpg
tayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmatylndh
lepwiqenggwdtfvelygnn

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.