PDB entry 3fcz

View 3fcz on RCSB PDB site
Description: Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility
Class: hydrolase
Keywords: metallo-beta-lactamase, antibiotic resistance, Hydrolase, Metal-binding, Zinc
Deposited on 2008-11-24, released 2008-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-29, with a file datestamp of 2020-01-24.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase 2
    Species: Bacillus cereus [TaxId:1396]
    Gene: blm
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04190 (0-211)
      • engineered (36)
      • engineered (76)
      • engineered (191)
      • engineered (203)
      • expression tag (212-221)
    Domains in SCOPe 2.08: d3fcza1, d3fcza2
  • Chain 'B':
    Compound: Beta-lactamase 2
    Species: Bacillus cereus [TaxId:1396]
    Gene: blm
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04190 (0-211)
      • engineered (36)
      • engineered (76)
      • engineered (191)
      • engineered (203)
      • expression tag (212-221)
    Domains in SCOPe 2.08: d3fczb1, d3fczb2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fczA (A:)
ktviknetgtisisqlnknvwvhtelgsfngeavpssglvlntskglvlvdsswddkltk
eliemvekkfqkrvtdaiithahadriggiktlkergikahstaltaelakkngyeeplg
dlqtvtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgnvaday
vnewstsienvskryrninavvpshgevgdkglllhtldllk

    Sequence, based on observed residues (ATOM records): (download) 
    >3fczA (A:)
ktviknetgtisisqlnknvwvhtelgsfavpssglvlntskglvlvdsswddkltkeli
emvekkfqkrvtdaiithahadriggiktlkergikahstaltaelakkngyeeplgdlq
tvtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgnvadayvne
wstsienvskryrninavvpshgevgdkglllhtldllk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3fczB (B:)
ktviknetgtisisqlnknvwvhtelgsfngeavpssglvlntskglvlvdsswddkltk
eliemvekkfqkrvtdaiithahadriggiktlkergikahstaltaelakkngyeeplg
dlqtvtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgnvaday
vnewstsienvskryrninavvpshgevgdkglllhtldllk

    Sequence, based on observed residues (ATOM records): (download) 
    >3fczB (B:)
ktviknetgtisisqlnknvwvhtelgsfavpssglvlntskglvlvdsswddkltkeli
emvekkfqkrvtdaiithahadriggiktlkergikahstaltaelakkngyeeplgdlq
tvtnlkfgnmkvetfypgkghtednivvwlpqynilvggclvkstsakdlgnvadayvne
wstsienvskryrninavvpshgevgdkglllhtldllk