PDB entry 3fc8
View 3fc8 on RCSB PDB site
Description: Crystal structure of transthyretin in complex with iododiflunisal-betaAlaOMe
Class: hormone binding protein
Keywords: transthyretin, amyloid, inhibitors, iodine, Polymorphism, Polyneuropathy, Retinol-binding, Secreted, HORMONE BINDING PROTEIN
Deposited on
2008-11-21, released
2009-02-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-17, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.196
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3fc8a_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d3fc8b_ - Heterogens: IFA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3fc8A (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtn
Sequence, based on observed residues (ATOM records): (download)
>3fc8A (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3fc8B (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtn
Sequence, based on observed residues (ATOM records): (download)
>3fc8B (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn