PDB entry 3faa

View 3faa on RCSB PDB site
Description: crystal structure of tgfbri complexed with a 2-aminoimidazole inhibitor
Deposited on 2008-11-16, released 2009-01-27
The last revision was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 3.35 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TGF-beta receptor type-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: TGF-beta receptor type-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: TGF-beta receptor type-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: TGF-beta receptor type-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: TGF-beta receptor type-1
    Species: Homo sapiens [TaxId:9606]
    Gene: TGFBR1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 55F, PO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3faaA (A:)
edpsldrpfisegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwr
gkwrgeevavkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsd
yhehgslfdylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilv
kkngtcciadlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradi
yamglvfweiarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqsc
ealrvmakimrecwyangaarltalrikktlsqlsqqegikm

    Sequence, based on observed residues (ATOM records):
    >3faaA (A:)
isegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwrgkwrgeeva
vkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsdyhehgslfd
ylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilvkkngtccia
dlglavrhdsatdtidinhrvgtkrymapevlddsinmkhfesfkradiyamglvfweia
rrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqscealrvmakimr
ecwyangaarltalrikktlsqlsqqeg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3faaB (B:)
edpsldrpfisegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwr
gkwrgeevavkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsd
yhehgslfdylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilv
kkngtcciadlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradi
yamglvfweiarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqsc
ealrvmakimrecwyangaarltalrikktlsqlsqqegikm

    Sequence, based on observed residues (ATOM records):
    >3faaB (B:)
isegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwrgkwrgeeva
vkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsdyhehgslfd
ylnrytvtvegmiklalstasglahlhmeigkpaiahrdlksknilvkkngtcciadlgl
avrhdsatdtidihrvgtkrymapevlddsinmkhfesfkradiyamglvfweiarrcsi
ggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqscealrvmakimrecwya
ngaarltalrikktlsqlsqqegi

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3faaC (C:)
edpsldrpfisegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwr
gkwrgeevavkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsd
yhehgslfdylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilv
kkngtcciadlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradi
yamglvfweiarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqsc
ealrvmakimrecwyangaarltalrikktlsqlsqqegikm

    Sequence, based on observed residues (ATOM records):
    >3faaC (C:)
isegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwrgkwrgeeva
vkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsdyhehgslfd
ylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilvkkngtccia
dlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradiyamglvfwe
iarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqscealrvmaki
mrecwyangaarltalrikktlsqlsqqeg

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3faaD (D:)
edpsldrpfisegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwr
gkwrgeevavkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsd
yhehgslfdylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilv
kkngtcciadlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradi
yamglvfweiarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqsc
ealrvmakimrecwyangaarltalrikktlsqlsqqegikm

    Sequence, based on observed residues (ATOM records):
    >3faaD (D:)
isegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwrgkwrgeeva
vkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsdyhehgslfd
ylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilvkkngtccia
dlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradiyamglvfwe
iarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqscealrvmaki
mrecwyangaarltalrikktlsqlsqqeg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >3faaE (E:)
edpsldrpfisegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwr
gkwrgeevavkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsd
yhehgslfdylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilv
kkngtcciadlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradi
yamglvfweiarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqsc
ealrvmakimrecwyangaarltalrikktlsqlsqqegikm

    Sequence, based on observed residues (ATOM records):
    >3faaE (E:)
isegttlkdliydmttsgsgsglpllvqrtiartivlqesigkgrfgevwrgkwrgeeva
vkifssreerswfreaeiyqtvmlrhenilgfiaadnkdngtwtqlwlvsdyhehgslfd
ylnrytvtvegmiklalstasglahlhmeivgtqgkpaiahrdlksknilvkkngtccia
dlglavrhdsatdtidiapnhrvgtkrymapevlddsinmkhfesfkradiyamglvfwe
iarrcsiggihedyqlpyydlvpsdpsveemrkvvceqklrpnipnrwqscealrvmaki
mrecwyangaarltalrikktlsqlsqqeg