PDB entry 3f8s

View 3f8s on RCSB PDB site
Description: Crystal structure of dipeptidyl peptidase IV in complex with inhibitor
Class: hydrolase
Keywords: Dipeptidyl peptidase 4, complex, Aminopeptidase, Glycoprotein, Hydrolase, Membrane, Protease, Secreted, Serine protease, Signal-anchor, Transmembrane
Deposited on 2008-11-13, released 2009-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dipeptidyl peptidase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP4, ADCP2, CD26
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3f8sa1, d3f8sa2
  • Chain 'B':
    Compound: dipeptidyl peptidase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: DPP4, ADCP2, CD26
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3f8sb1, d3f8sb2
  • Heterogens: NAG, PF2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f8sA (A:)
gtddatadsrktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvfl
enstfdefghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripn
ntqwvtwspvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsa
ysalwwspngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffv
vntdslssvtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdy
dessgrwnclvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqid
kkdctfitkgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclsceln
percqyysvsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmp
skkldfiilnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylast
eniivasfdgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgws
yggyvtsmvlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvms
raenfkqveyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqh
iythmshfikqcfslplvprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3f8sA (A:)
srktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdef
ghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtws
pvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslss
vtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwn
clvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfit
kgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyys
vsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfii
lnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsm
vlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshf
ikqcfslp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f8sB (B:)
gtddatadsrktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvfl
enstfdefghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripn
ntqwvtwspvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsa
ysalwwspngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffv
vntdslssvtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdy
dessgrwnclvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqid
kkdctfitkgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclsceln
percqyysvsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmp
skkldfiilnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylast
eniivasfdgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgws
yggyvtsmvlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvms
raenfkqveyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqh
iythmshfikqcfslplvprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3f8sB (B:)
srktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdef
ghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtws
pvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslss
vtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwn
clvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfit
kgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyys
vsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfii
lnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsm
vlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshf
ikqcfslp