PDB entry 3f8j

View 3f8j on RCSB PDB site
Description: Mouse UHRF1 SRA domain bound with hemi-methylated CpG, crystal structure in space group C222(1)
Class: ligase/DNA
Keywords: UHRF1, SRA, base flipping, 5-methylcytosine, CpG methylation, Cell cycle, Developmental protein, DNA damage, DNA repair, DNA-binding, Ligase, Metal-binding, Nucleus, Phosphoprotein, Transcription, Transcription regulation, Ubl conjugation pathway, Zinc-finger, LIGASE-DNA COMPLEX
Deposited on 2008-11-12, released 2009-01-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: 0.198
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: E3 ubiquitin-protein ligase UHRF1
    Species: Mus musculus [TaxId:10090]
    Gene: Uhrf1, Np95
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3f8jb_
  • Chain 'F':
    Compound: 5'-d(*dcp*dcp*dap*dtp*dgp*(5cm)p*dgp*dcp*dtp*dgp*dap*dc)-3'
    Species: synthetic, synthetic
  • Chain 'G':
    Compound: 5'-d(*dgp*dtp*dcp*dap*dgp*dcp*dgp*dcp*dap*dtp*dgp*dg)-3'
    Species: synthetic, synthetic
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f8jB (B:)
ivpanhfgpipgvpvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvd
ngnyftytgsggrdlsgnkrtagqssdqkltnnnralalnchspinekgaeaedwrqgkp
vrvvrnmkggkhskyapaegnrydgiykvvkywpergksgflvwryllrrddtepepwtr
egkdrtrqlgltmqypegylealankeksrkr

    Sequence, based on observed residues (ATOM records): (download) 
    >3f8jB (B:)
ivpanhfgpipgvpvgtmwrfrvqvsesgvhrphvagihgrsndgayslvlaggyeddvd
ngnyftytgsggrdlsgnkrtagqssdqkltnnnralalnchspinekgaeaedwrqgkp
vrvvrnmkggkhskyapaegnrydgiykvvkywpergksgflvwryllrrddtepepwtr
egkdrtrqlgltmqypegylealank

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.