PDB entry 3f7u

View 3f7u on RCSB PDB site
Description: Crystal Structure of soluble domain of CA4 in complex with small molecule.
Class: lyase
Keywords: Structure-based drug design. Small molecule complex. CO-CRYSTAL., Cell membrane, Disease mutation, Glycoprotein, GPI-anchor, Lipoprotein, Lyase, Membrane, Metal-binding, Retinitis pigmentosa, Sensory transduction, Vision, Zinc
Deposited on 2008-11-10, released 2009-09-22
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-05-12, with a file datestamp of 2010-05-07.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.214
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3f7ua_
  • Chain 'B':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3f7ub_
  • Chain 'C':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3f7uc_
  • Chain 'D':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3f7ud_
  • Heterogens: ZN, AG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f7uA (A:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >3f7uA (A:)
wcyevqaesclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtwtvqnn
ghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhivheke
kpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaesslldllpkeeklrhy
frylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvsmkdnvrplqqlg
qrtviks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f7uB (B:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >3f7uB (B:)
wcyevqaesclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtwtvqnn
ghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhivheke
kpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaesslldllpkeeklrhy
frylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvsmkdnvrplqqlg
qrtviks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3f7uC (C:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >3f7uC (C:)
wcyevqaesclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtwtvqnn
ghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhivheke
kpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaesslldllpkeeklrhy
frylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvsmkdnvrplqqlg
qrtviks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3f7uD (D:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >3f7uD (D:)
wcyevqaesclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtwtvqnn
ghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhivheke
kpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaesslldllpkeeklrhy
frylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvsmkdnvrplqqlg
qrtviks