PDB entry 3f62

View 3f62 on RCSB PDB site
Description: Crystal Structure of Human IL-18 in complex with Ectromelia virus IL-18 Binding Protein
Class: cytokine
Keywords: immunoglobulin, IL-18, beta trefoil, Cytokine, Secreted
Deposited on 2008-11-05, released 2009-01-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.191
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Interleukin 18 binding protein
    Species: Ectromelia virus [TaxId:12643]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9IW12 (3-End)
      • expression tag (0-2)
  • Chain 'B':
    Compound: Interleukin-18
    Species: Homo sapiens [TaxId:9606]
    Gene: IL18, IGIF, IL1F4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14116 (1-End)
      • expression tag (0)
      • engineered (68)
      • engineered (76)
      • engineered (127)
    Domains in SCOPe 2.08: d3f62b1, d3f62b2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f62B (B:)
gyfgklesklsvirnlndqvlfidqgnrplfedmtdsdsrdnaprtifiismykdsqprg
mavtisvksekistlssenkiisfkemnppdnikdtksdiiffqrsvpghdnkmqfesss
yegyflasekerdlfklilkkedelgdrsimftvqned

    Sequence, based on observed residues (ATOM records): (download) 
    >3f62B (B:)
gyfgklesklsvirnlndqvlfidqgnrplfedaprtifiismykdsqprgmavtisvks
ekistlssenkiisfkemnppdnikdtksdiiffqrsvpghdnkmqfesssyegyflase
klfklilkkedelgdrsimftvqne