PDB entry 3f2r

View 3f2r on RCSB PDB site
Description: Crystal structure of human choline kinase alpha in complex with hemicholinium-3
Class: transferase
Keywords: NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS Consortium, SGC, hemicholinium-3, Alternative splicing, Cytoplasm, Kinase, Transferase
Deposited on 2008-10-30, released 2008-11-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: choline kinase alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CHKA, CHK, CKI
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35790
      • variant (163)
      • variant (365)
    Domains in SCOPe 2.08: d3f2ra_
  • Chain 'B':
    Compound: choline kinase alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CHKA, CHK, CKI
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35790 (Start-400)
      • variant (163)
      • variant (365)
    Domains in SCOPe 2.08: d3f2rb_
  • Heterogens: HC6, UNX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f2rA (A:)
gsshhhhhhssglvprgspqppadeqpeprtrrraylwckeflpgawrglredefhisvi
rgglsnmlfqcslpdttatlgdeprkvllrlygailqmrscnkegseqaqkenefqgaea
mvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisaeiaekmatfh
gmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplelenlrsllest
pspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignhfcewmydysy
ekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeemllevnrfalas
hflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

    Sequence, based on observed residues (ATOM records): (download) 
    >3f2rA (A:)
eqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgdep
rkvllrlygamvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisa
eiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplel
enlrsllestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignh
fcewmydysyekypffranirkyptkkqqlhfissylpafqdfenlsteeksiikeemll
evnrfalashflwglwsivqakissiefgymdyaqarfdayfhqkrkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f2rB (B:)
gsshhhhhhssglvprgspqppadeqpeprtrrraylwckeflpgawrglredefhisvi
rgglsnmlfqcslpdttatlgdeprkvllrlygailqmrscnkegseqaqkenefqgaea
mvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisaeiaekmatfh
gmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplelenlrsllest
pspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignhfcewmydysy
ekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeemllevnrfalas
hflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

    Sequence, based on observed residues (ATOM records): (download) 
    >3f2rB (B:)
raylwckeflpawmlfqcrkvllrlmvlesvmfailaerslgpklygifpqgrleqfips
rrldteelslpdisaeiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesri
kklhkllsynlplelenlrsllestpspvvfchndcqegnilllegrensekqklmlidf
eyssynyrgfdignhfcewmydysyekypffranirkyptkkqqlhfissylpafqndfe
nlsteeksiikeemllevnrfalashflwglwsivqakissiefgymdyaqarfdayfhq
krklgv