PDB entry 3f2a

View 3f2a on RCSB PDB site
Description: Crystal structure of human Pim-1 in complex with DAPPA
Class: transferase
Keywords: potein kinase fold, Alternative initiation, ATP-binding, Cell membrane, Cytoplasm, Kinase, Manganese, Membrane, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Serine/threonine-protein kinase, Transferase
Deposited on 2008-10-29, released 2009-03-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-04-21, with a file datestamp of 2009-04-17.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.256
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Proto-oncogene serine/threonine-protein kinase Pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3f2aa_
  • Heterogens: 985, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f2aA (A:)
aapcndlhatklapgkekeplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdr
isdwgelpngtrvpmevvllkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfi
tergalqeelarsffwqvleavrhchncgvlhrdikdenilidlnrgelklidfgsgall
kdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqv
ffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >3f2aA (A:)
eplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevv
llkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqv
leavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppe
wiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcl
alrpsdrptfeeiqnhpwmqdvllpqetaeihlhsls