PDB entry 3f22

View 3f22 on RCSB PDB site
Description: Crystal structure of Zalpha in complex with d(CGTACG)
Class: hydrolase
Keywords: Protein-Z-DNA complex, Alternative promoter usage, Alternative splicing, Cytoplasm, Disease mutation, DNA-binding, Hydrolase, Metal-binding, mRNA processing, Nucleus, Phosphoprotein, Polymorphism, RNA-binding, RNA-mediated gene silencing, Ubl conjugation, Zinc
Deposited on 2008-10-28, released 2008-12-30
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-10, with a file datestamp of 2009-02-06.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.224
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Double-stranded RNA-specific adenosine deaminase
    Species: Homo sapiens [TaxId:9606]
    Gene: ADAR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3f22a_
  • Chain 'B':
    Compound: Double-stranded RNA-specific adenosine deaminase
    Species: Homo sapiens [TaxId:9606]
    Gene: ADAR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3f22b_
  • Chain 'C':
    Compound: Double-stranded RNA-specific adenosine deaminase
    Species: Homo sapiens [TaxId:9606]
    Gene: ADAR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3f22c_
  • Chain 'D':
    Compound: DNA (5'-d(*dtp*dcp*dgp*dtp*dap*dcp*dg)-3')
    Species: synthetic, synthetic
  • Chain 'E':
    Compound: DNA (5'-d(*dtp*dcp*dgp*dtp*dap*dcp*dg)-3')
    Species: synthetic, synthetic
  • Chain 'F':
    Compound: DNA (5'-d(*dtp*dcp*dgp*dtp*dap*dcp*dg)-3')
    Species: synthetic, synthetic
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f22A (A:)
gshmlsiyqdqeqrilkfleelgegkattahdlsgklgtpkkeinrvlyslakkgklqke
agtpplwkiavstqawnqhsg

    Sequence, based on observed residues (ATOM records): (download) 
    >3f22A (A:)
siyqdqeqrilkfleelgegkattahdlsgklgtpkkeinrvlyslakkgklqkeagtpp
lwkia

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f22B (B:)
gshmlsiyqdqeqrilkfleelgegkattahdlsgklgtpkkeinrvlyslakkgklqke
agtpplwkiavstqawnqhsg

    Sequence, based on observed residues (ATOM records): (download) 
    >3f22B (B:)
qdqeqrilkfleelgegkattahdlsgklgtpkkeinrvlyslakkgklqkeagtpplwk
ia

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3f22C (C:)
gshmlsiyqdqeqrilkfleelgegkattahdlsgklgtpkkeinrvlyslakkgklqke
agtpplwkiavstqawnqhsg

    Sequence, based on observed residues (ATOM records): (download) 
    >3f22C (C:)
siyqdqeqrilkfleelgegkattahdlsgklgtpkkeinrvlyslakkgklqkeagtpp
lwkiav

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.