PDB entry 3f0t

View 3f0t on RCSB PDB site
Description: Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT
Class: transferase
Keywords: Transferase, thymidine kinase, DNA-synthesis, PET tracer, ATP-binding, DNA synthesis, Early protein, Nucleotide-binding
Deposited on 2008-10-26, released 2009-11-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-10-02, with a file datestamp of 2013-09-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.195
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: Herpes simplex virus (type 1 / strain 17) [TaxId:10299]
    Gene: TK, UL23
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3f0ta_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: Herpes simplex virus (type 1 / strain 17) [TaxId:10299]
    Gene: TK, UL23
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3f0tb_
  • Heterogens: SO4, NCV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f0tA (A:)
kmptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttq
hrldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrh
piaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpg
erldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphi
gdtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlt
sgmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >3f0tA (A:)
kmptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttq
hrldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeapppaltlifdrhpiaal
lcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldl
amlaairrvygllantvrylqcggswredwgqlsgprphigdtlftlfrapellapngdl
ynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdl
artfaremg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3f0tB (B:)
kmptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttq
hrldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrh
piaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpg
erldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphi
gdtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlt
sgmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >3f0tB (B:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeapppaltlifdrhpiaall
cypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrpgerldlaml
aairrvygllantvrylqcggswredwgqlsgpqsnagprphigdtlftlfrapellapn
gdlynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipti
cdlartfaremge