PDB entry 3ezv
View 3ezv on RCSB PDB site
Description: CDK-2 with indazole inhibitor 9 bound at its active site
Class: transferase
Keywords: KINASE, PKC, PROTEIN KINASE, INHIBITOR, ATP-binding, Cell cycle, Cell division, Mitosis, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Transferase
Deposited on
2008-10-23, released
2009-02-03
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-03, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: 0.228
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Gene: CDK2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d3ezva_ - Heterogens: EZV, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3ezvA (A:)
gsmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkel
nhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafc
hshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgck
yystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykp
sfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>3ezvA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirvpstaireisllkelnhpnivkll
dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfglvvtlwyrapeillgckyystavdiwslgcifaemvtrra
lfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrs
llsqmlhydpnkrisakaalahpffqdvtkpvphlrl