PDB entry 3ez3

View 3ez3 on RCSB PDB site
Description: crystal structure of plasmodium vivax geranylgeranylpyrophosphate synthase pvx_092040 with zoledronate and ipp bound
Deposited on 2008-10-22, released 2008-12-02
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Farnesyl pyrophosphate synthase, putative
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVX_092040
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5K4U6 (Start-395)
      • see remark 999 (133)
      • see remark 999 (226)
  • Chain 'B':
    Compound: Farnesyl pyrophosphate synthase, putative
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVX_092040
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5K4U6 (Start-395)
      • see remark 999 (133)
      • see remark 999 (226)
  • Chain 'C':
    Compound: Farnesyl pyrophosphate synthase, putative
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVX_092040
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5K4U6 (Start-395)
      • see remark 999 (133)
      • see remark 999 (226)
  • Chain 'D':
    Compound: Farnesyl pyrophosphate synthase, putative
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVX_092040
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5K4U6 (Start-395)
      • see remark 999 (133)
      • see remark 999 (226)
  • Heterogens: ZOL, IPE, MG, EDO, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ez3A (A:)
mgsshhhhhhssgrenlyfqgmketnseeadsglaffrnmydkyrdaflshlneysleee
ikehiskyykllfdynclggknnrgilviliyeyvknrdinssewekaaclawcieilqa
aflvaddimdkgemrrnkycwyllkdvetknavndvlllynsiyklieiylrnescyvdv
iatfrdatlktiigqhldtnifsdkysdahreidvnninvpeqpvidinminfgvykniv
ihktayysfflpivcgmllagiavdnliykkiedismlmgeyfqihddyldifgdstktg
kvgsdiqnnkltwpliktfelcsepdkikivknygknnlacvkvidslyeqykirkhyes
yekaqkakilsainelhhegieyvlkylleilftgv

    Sequence, based on observed residues (ATOM records):
    >3ez3A (A:)
laffrnmydkyrdaflshlneysleeeikehiskyykllfdynclggknnrgilviliye
yvknrinssewekaaclawcieilqaaflvaddimdkgemrrnkycwyllkdvetknavn
dvlllynsiyklieiylrnescyvdviatfrdatlktiigqhldtnifsdkyseidvnni
nvpeqpvidinminfgvyknivihktayysfflpivcgmllagiavdnliykkiedisml
mgeyfqihddyldifgdstktgkvgsdiqnnkltwpliktfelcsepdkikivknygknn
lacvkvidslyeqykirkhyesyekaqkakilsainelhhegieyvlkylleilftgv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ez3B (B:)
mgsshhhhhhssgrenlyfqgmketnseeadsglaffrnmydkyrdaflshlneysleee
ikehiskyykllfdynclggknnrgilviliyeyvknrdinssewekaaclawcieilqa
aflvaddimdkgemrrnkycwyllkdvetknavndvlllynsiyklieiylrnescyvdv
iatfrdatlktiigqhldtnifsdkysdahreidvnninvpeqpvidinminfgvykniv
ihktayysfflpivcgmllagiavdnliykkiedismlmgeyfqihddyldifgdstktg
kvgsdiqnnkltwpliktfelcsepdkikivknygknnlacvkvidslyeqykirkhyes
yekaqkakilsainelhhegieyvlkylleilftgv

    Sequence, based on observed residues (ATOM records):
    >3ez3B (B:)
ffrnmydkyrdaflshlneysleeeikehiskyykllfdynclggknnrgilviliyeyv
knssewekaaclawcieilqaaflvaddimdkgemrrnkycwyllkdvetknavndvlll
ynsiyklieiylrnescyvdviatfrdatlktiigqhldtnifsdkyshreidvnninvp
eqpvidinminfgvyknivihktayysfflpivcgmllagianliykkiedismlmgeyf
qihddyldifgdstktgkvgsdiqnnkltwpliktfelcsepdkikivknygknnlacvk
vidslyeqykirkhyesyekaqkakilsainelhhegieyvlkylleilftgv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3ez3C (C:)
mgsshhhhhhssgrenlyfqgmketnseeadsglaffrnmydkyrdaflshlneysleee
ikehiskyykllfdynclggknnrgilviliyeyvknrdinssewekaaclawcieilqa
aflvaddimdkgemrrnkycwyllkdvetknavndvlllynsiyklieiylrnescyvdv
iatfrdatlktiigqhldtnifsdkysdahreidvnninvpeqpvidinminfgvykniv
ihktayysfflpivcgmllagiavdnliykkiedismlmgeyfqihddyldifgdstktg
kvgsdiqnnkltwpliktfelcsepdkikivknygknnlacvkvidslyeqykirkhyes
yekaqkakilsainelhhegieyvlkylleilftgv

    Sequence, based on observed residues (ATOM records):
    >3ez3C (C:)
laffrnmydkyrdaflshlneysleeeikehiskyykllfdynclggknnrgilviliye
yvkninssewekaaclawcieilqaaflvaddimdkgemrrnkycwyllkdvetknavnd
vlllynsiyklieiylrnescyvdviatfrdatlktiigqhldtnifsdkyseidvnnin
vpeqpvidinminfgvyknivihktayysfflpivcgmllagiavdnliykkiedismlm
geyfqihddyldifgdstktgkvgsdiqnnkltwpliktfelcsepdkikivknygknnl
acvkvidslyeqykirkhyesyekaqkakilsainelhhegieyvlkylleilftgv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3ez3D (D:)
mgsshhhhhhssgrenlyfqgmketnseeadsglaffrnmydkyrdaflshlneysleee
ikehiskyykllfdynclggknnrgilviliyeyvknrdinssewekaaclawcieilqa
aflvaddimdkgemrrnkycwyllkdvetknavndvlllynsiyklieiylrnescyvdv
iatfrdatlktiigqhldtnifsdkysdahreidvnninvpeqpvidinminfgvykniv
ihktayysfflpivcgmllagiavdnliykkiedismlmgeyfqihddyldifgdstktg
kvgsdiqnnkltwpliktfelcsepdkikivknygknnlacvkvidslyeqykirkhyes
yekaqkakilsainelhhegieyvlkylleilftgv

    Sequence, based on observed residues (ATOM records):
    >3ez3D (D:)
frnmydkyrdaflshlneysleeeikehiskyykllfdynclggknnrgilviliyeyvk
nssewekaaclawcieilqaaflvaddimdkgemrrnkycwyllkdvetknavndvllly
nsiyklieiylrnescyvdviatfrdatlktiigqhldtnifsdkyshreidvnninvpe
qpvidinminfgvyknivihktayysfflpivcgmllagidnliykkiedismlmgeyfq
ihddyldifgdstktgkvgsdiqnnkltwpliktfelcsepdkikivknygknnlacvkv
idslyeqykirkhyesyekaqkakilsainelhegieyvlkylleilftgv