PDB entry 3eyl

View 3eyl on RCSB PDB site
Description: Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound
Class: ligase
Keywords: Apoptosis,Smac-mimetics,Zinc-finger, Ligase, Metal-binding, Phosphoprotein, Protease inhibitor, Thiol protease inhibitor, Ubl conjugation pathway
Deposited on 2008-10-21, released 2008-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.191
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: baculoviral iap repeat-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC4, API3, IAP3, XIAP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3eyla_
  • Chain 'B':
    Compound: baculoviral iap repeat-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BIRC4, API3, IAP3, XIAP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3eylb_
  • Heterogens: ZN, SMK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eylA (A:)
sdavssdrnfpnstnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkc
fhcgggltdwkpsedpweqhakwypgckylleqkgqeyinnihlthsleeclvrtthhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >3eylA (A:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleeclvr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3eylB (B:)
sdavssdrnfpnstnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkc
fhcgggltdwkpsedpweqhakwypgckylleqkgqeyinnihlthsleeclvrtthhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >3eylB (B:)
tnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkps
edpweqhakwypgckylleqkgqeyinnihlthsleeclvr