PDB entry 3eyh

View 3eyh on RCSB PDB site
Description: Crystal structures of JAK1 and JAK2 inhibitor complexes
Class: transferase
Keywords: JAK kinase, ATP-binding, Kinase, Nucleotide-binding, Phosphoprotein, SH2 domain, Transferase, Tyrosine-protein kinase
Deposited on 2008-10-20, released 2009-02-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-12-29, with a file datestamp of 2009-12-24.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.178
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK1, hCG_22179
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d3eyha_
  • Heterogens: IZA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eyhA (A:)
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadlkk
eieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlkya
vqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdsp
vfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrl
vntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

    Sequence, based on observed residues (ATOM records): (download) 
    >3eyhA (A:)
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpenhiadlkkeie
ilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlkyavqi
ckgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfw
yapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvnt
lkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk