PDB entry 3exj

View 3exj on RCSB PDB site
Description: Crystal Structure of a p53 Core Tetramer Bound to DNA
Class: transcription/DNA
Keywords: protein-DNA complex, Acetylation, Activator, Anti-oncogene, Apoptosis, Cell cycle, Covalent protein-RNA linkage, Cytoplasm, Disease mutation, DNA-binding, Endoplasmic reticulum, Metal-binding, Methylation, Nucleus, Phosphoprotein, Transcription, Transcription regulation, Ubl conjugation, Zinc, TRANSCRIPTION/DNA COMPLEX
Deposited on 2008-10-16, released 2008-12-16
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-03, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.225
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mouse p53 core domain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3exja_
  • Chain 'B':
    Compound: mouse p53 core domain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3exjb_
  • Chain 'C':
    Compound: 5'-d(p*dgp*dap*dgp*dcp*dap*dtp*dgp*dcp*dtp*dcp*da)-3'
  • Chain 'D':
    Compound: 5'-d(*dtp*dtp*dgp*dap*dgp*dcp*dap*dtp*dgp*dcp*dtp*dc)-3'
  • Heterogens: ZN, FLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3exjA (A:)
sqktyqgnygfhlgflqsgtaksvmctyspplnklfcqlaktcpvqlwvsatppagsrvr
amaiykksqhmtevvrrcphhercsdgdglappqhlirvegnlypeyledrqtfrhsvvv
pyeppeagseyttihykymcnsscmggmnrrpiltiitledssgnllgrdsfevrvcacp
grdrrteeenfrkkevl

    Sequence, based on observed residues (ATOM records): (download) 
    >3exjA (A:)
ktyqgnygfhlgflqsgtaksvmctyspplnklfcqlaktcpvqlwvsatppagsrvram
aiykksqhmtevvrrcphhercsdgdglappqhlirvegnlypeyledrqtfrhsvvvpy
eppeagseyttihykymcnsscmggmnrrpiltiitledssgnllgrdsfevrvcacpgr
drrteeenfrkkev

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3exjB (B:)
sqktyqgnygfhlgflqsgtaksvmctyspplnklfcqlaktcpvqlwvsatppagsrvr
amaiykksqhmtevvrrcphhercsdgdglappqhlirvegnlypeyledrqtfrhsvvv
pyeppeagseyttihykymcnsscmggmnrrpiltiitledssgnllgrdsfevrvcacp
grdrrteeenfrkkevl

    Sequence, based on observed residues (ATOM records): (download) 
    >3exjB (B:)
sqktyqgnygfhlgflqsgtaksvmctyspplnklfcqlaktcpvqlwvsatppagsrvr
amaiykksqhmtevvrrcphhercsdgdglappqhlirvegnlypeyledrqtfrhsvvv
pyeppeagseyttihykymcnsscmggmnrrpiltiitledssgnllgrdsfevrvcacp
grdrrteeenfrkk

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.