PDB entry 3eww

View 3eww on RCSB PDB site
Description: d312n mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-ump, covalent adduct
Deposited on 2008-10-16, released 2009-04-07
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: N/A
AEROSPACI score: 0.72 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Orotidine-5'-phosphate decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: UMPS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11172 (3-259)
      • expression tag (0-2)
      • engineered mutation (91)
  • Chain 'B':
    Compound: Orotidine-5'-phosphate decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: UMPS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11172 (3-259)
      • expression tag (0-2)
      • engineered mutation (91)
  • Heterogens: GOL, U1P, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ewwA (A:)
gamelsfgaraelprihpvaskllrlmqkketnlclsadvslarellqladalgpsicml
kthvdilndftldvmkelitlakcheflifenrkfadigntvkkqyeggifkiaswadlv
nahvvpgsgvvkglqevglplhrgclliaemsstgslatgdytraavrmaeehsefvvgf
isgsrvsmkpeflhltpgvqleaggdnlgqqynspqevigkrgsdiiivgrgiisaadrl
eaaemyrkaaweaylsrlgv

    Sequence, based on observed residues (ATOM records):
    >3ewwA (A:)
melsfgaraelprihpvaskllrlmqkketnlclsadvslarellqladalgpsicmlkt
hvdilndftldvmkelitlakcheflifenrkfadigntvkkqyeggifkiaswadlvna
hvvpgsgvvkglqevglplhrgclliaemsstgslatgdytraavrmaeehsefvvgfis
gsrvsmkpeflhltpgvqleaggdnlgqqynspqevigkrgsdiiivgrgiisaadrlea
aemyrkaaweaylsrlg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ewwB (B:)
gamelsfgaraelprihpvaskllrlmqkketnlclsadvslarellqladalgpsicml
kthvdilndftldvmkelitlakcheflifenrkfadigntvkkqyeggifkiaswadlv
nahvvpgsgvvkglqevglplhrgclliaemsstgslatgdytraavrmaeehsefvvgf
isgsrvsmkpeflhltpgvqleaggdnlgqqynspqevigkrgsdiiivgrgiisaadrl
eaaemyrkaaweaylsrlgv

    Sequence, based on observed residues (ATOM records):
    >3ewwB (B:)
melsfgaraelprihpvaskllrlmqkketnlclsadvslarellqladalgpsicmlkt
hvdilndftldvmkelitlakcheflifenrkfadigntvkkqyeggifkiaswadlvna
hvvpgsgvvkglqevglplhrgclliaemsstgslatgdytraavrmaeehsefvvgfis
gsrvsmkpeflhltpgvqleaggdnlgqqynspqevigkrgsdiiivgrgiisaadrlea
aemyrkaaweaylsrlg