PDB entry 3ew3

View 3ew3 on RCSB PDB site
Description: the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor
Deposited on 2008-10-14, released 2009-11-03
The last revision was dated 2010-04-28, with a file datestamp of 2010-04-23.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: 0.256
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prolactin
    Species: Homo sapiens [TaxId:9606]
    Gene: PRL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01236 (18-End)
      • see remark 999 (3-17)
  • Chain 'B':
    Compound: Prolactin receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: PRLR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05710 (1-End)
      • initiating methionine (0)
  • Chain 'C':
    Compound: Prolactin receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: PRLR
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ew3A (A:)
maqhppycrnqpgkcqiplrdlfdravvlshyihnlssemfsefdkrythgrgfitkain
schtsslatpedkeqaqqmnqkdflslivsilrswneplyhlvtevrgmqeapeailska
veieeqtkrllegmelivsqvhpetkeneiypvwsglpslqmadeesrlsayynllhclr
rdshkidnylkllkcriihnnnc

    Sequence, based on observed residues (ATOM records):
    >3ew3A (A:)
hppycrnqpgkcqiplrdlfdravvlshyihnlssemfsefdkryttkainschtsslat
pedkeqaqqmnqkdflslivsilrswneplyhlvtevrgmqeapeailskaveieeqtkr
llegmelivsqvhpneiypvwsglpsldeesrlsayynllhclrrdshkidnylkllkcr
iihnn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ew3B (B:)
mqsppgkpeihkcrspdketftcwwnpgtdgglptnysltyskegekttyecpdyktsgp
nscffskqytsiwkiyiitvnatnqmgssssdplyvdvtyivepepprnltlevkqlkdk
ktylwvkwspptitdvktgwftmeyeirlkpeeaeeweihftghqtqfkvfdlypgqkyl
vqtrckpdhgywsrwsqessvempndftlkdrsrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ew3B (B:)
mqsppgkpeihkcrspdketftcwwnpgtdgglptnysltyskegekttyecpdyktsgp
nscffskqytsiwkiyiitvnatnqmgssssdplyvdvtyivepepprnltlevkqlkdk
ktylwvkwspptitdvktgwftmeyeirlkpeeaeeweihftghqtqfkvfdlypgqkyl
vqtrckpdhgywsrwsqessvem

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3ew3C (C:)
mqsppgkpeihkcrspdketftcwwnpgtdgglptnysltyskegekttyecpdyktsgp
nscffskqytsiwkiyiitvnatnqmgssssdplyvdvtyivepepprnltlevkqlkdk
ktylwvkwspptitdvktgwftmeyeirlkpeeaeeweihftghqtqfkvfdlypgqkyl
vqtrckpdhgywsrwsqessvempndftlkdrsrshhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ew3C (C:)
pgkpeihkcrspdketftcwwnpglptnysltyskegekttyecpdyktsgpnscffskq
ytsiwkiyiitvnatnqmgssssdplyvdvtyivepepprnltlevkktylwvkwsppti
tmeyeirlkpeeaeeweihftghqtqfkvfdlypgqkylvqtrckpdhgywsrwsqessv
e