PDB entry 3evj

View 3evj on RCSB PDB site
Description: Intermediate structure of antithrombin bound to the natural pentasaccharide
Class: HYDROLASE inhibitor
Keywords: serpin, heparin, Blood coagulation, Disease mutation, Glycoprotein, Heparin-binding, Protease inhibitor, Secreted, Serine protease inhibitor, Thrombophilia, HYDROLASE inhibitor
Deposited on 2008-10-13, released 2008-10-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.231
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'I':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3evji_
  • Chain 'L':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3evjl_
  • Heterogens: NAG, NTO, HOH

PDB Chain Sequences:

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >3evjI (I:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3evjI (I:)
    dictakprdipmnpmciyrspkipeatnrrvwelskansrfattfyqhladskndndnif
    lsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkassk
    lvsanrlfgdksltfnetyqdiselvygaklqpldaeqsraainkwvsnktegritdvip
    seaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfryrrv
    aegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhmprf
    riedgfslkeqlqdmglvdlfspeksklpgivadlyvsdafhkaflevneegseaaasta
    vviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >3evjL (L:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >3evjL (L:)
    vdictakprdipmnpmciyregseqkipeatnrrvwelskansrfattfyqhladskndn
    dniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrk
    ankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnk
    tegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmy
    qegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldelee
    mmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkafl
    evneegseaaastavviagrslpnrvtfkanrpflvfirevplntiifmgrvanpcv