PDB entry 3eub

View 3eub on RCSB PDB site
Description: Crystal Structure of Desulfo-Xanthine Oxidase with Xanthine
Class: oxidoreductase
Keywords: enzyme catalysis, desulfo, substrate orientation, xanthine, FAD, Flavoprotein, Iron, Iron-sulfur, Metal-binding, Molybdenum, NAD, Oxidoreductase, Peroxisome
Deposited on 2008-10-09, released 2009-01-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-09-17, with a file datestamp of 2014-09-12.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.217
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '2':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eub21, d3eub22
  • Chain '3':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eub31, d3eub32
  • Chain '4':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eub41, d3eub42
  • Chain 'A':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3euba1, d3euba2
  • Chain 'B':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubb1, d3eubb2
  • Chain 'C':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubc1, d3eubc2
  • Chain 'J':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubj1, d3eubj2
  • Chain 'K':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubk1, d3eubk2
  • Chain 'L':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubl1, d3eubl2
  • Chain 'S':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubs1, d3eubs2
  • Chain 'T':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubt1, d3eubt2
  • Chain 'U':
    Compound: Xanthine dehydrogenase/oxidase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3eubu1, d3eubu2
  • Heterogens: FES, MTE, MOM, FAD, XAN

PDB Chain Sequences:

  • Chain '2':
    Sequence, based on SEQRES records: (download) 
    >3eub2 (2:)
mtadelvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydr
lqdkiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgi
vmsmytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

    Sequence, based on observed residues (ATOM records): (download) 
    >3eub2 (2:)
tadelvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydrl
qdkiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgiv
msmytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3eub3 (3:)
pkqlrfegervtwiqastlkelldlkaqhpeaklvvgnteigiemkfknqlfpmiicpaw
ipelnavehgpegisfgaacalssvektlleavaklptqktevfrgvleqlrwfagkqvk
svaslggniitaspisdlnpvfmasgtkltivsrgtrrtvpmdhtffpsyrktllgpeei
llsieipysredeffsafkqasrreddiakvtcgmrvlfqpgsmqvkelalcyggmadrt
isalkttqkqlskfwnekllqdvcaglaeelslspdapggmiefrrtltlsfffkfyltv
lkklg

  • Chain '4':
    Sequence, based on SEQRES records: (download) 
    >3eub4 (4:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkfttlcvtgapgnckpwslrv

    Sequence, based on observed residues (ATOM records): (download) 
    >3eub4 (4:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkfttlcvtgapgnck

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eubA (A:)
mtadelvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydr
lqdkiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgi
vmsmytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubA (A:)
delvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydrlqd
kiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgivms
mytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3eubB (B:)
pkqlrfegervtwiqastlkelldlkaqhpeaklvvgnteigiemkfknqlfpmiicpaw
ipelnavehgpegisfgaacalssvektlleavaklptqktevfrgvleqlrwfagkqvk
svaslggniitaspisdlnpvfmasgtkltivsrgtrrtvpmdhtffpsyrktllgpeei
llsieipysredeffsafkqasrreddiakvtcgmrvlfqpgsmqvkelalcyggmadrt
isalkttqkqlskfwnekllqdvcaglaeelslspdapggmiefrrtltlsfffkfyltv
lkklg

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubB (B:)
pkqlrfegervtwiqastlkelldlkaqhpeaklvvgnteigiemkfknqlfpmiicpaw
ipelnavehgpegisfgaacalssvektlleavaklptqktevfrgvleqlrwfagkqvk
svaslggniitaspisdlnpvfmasgtkltivsrgtrrtvpmdhtffpsyrktllgpeei
llsieipysredeffsafkqasrreddiakvtcgmrvlfqpgsmqvkelalcyggmadrt
isalkttqkqlskfwnekllqdvcaglaeelslspdapggmiefrrtltlsfffkfyltv
lkkl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3eubC (C:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkfttlcvtgapgnckpwslrv

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubC (C:)
tvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpgf
vcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtyed
lpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethctia
ipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsva
valaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagnsr
dlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmseva
vtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnken
cwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqvas
kalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpdg
swedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgdh
knlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykipa
fgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnntk
elfrldspatpekirnacvdkfttlcvtgapgn

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3eubJ (J:)
mtadelvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydr
lqdkiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgi
vmsmytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubJ (J:)
delvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydrlqd
kiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgivms
mytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >3eubK (K:)
pkqlrfegervtwiqastlkelldlkaqhpeaklvvgnteigiemkfknqlfpmiicpaw
ipelnavehgpegisfgaacalssvektlleavaklptqktevfrgvleqlrwfagkqvk
svaslggniitaspisdlnpvfmasgtkltivsrgtrrtvpmdhtffpsyrktllgpeei
llsieipysredeffsafkqasrreddiakvtcgmrvlfqpgsmqvkelalcyggmadrt
isalkttqkqlskfwnekllqdvcaglaeelslspdapggmiefrrtltlsfffkfyltv
lkklg

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubK (K:)
qlrfegervtwiqastlkelldlkaqhpeaklvvgnteigiemkfknqlfpmiicpawip
elnavehgpegisfgaacalssvektlleavaklptqktevfrgvleqlrwfagkqvksv
aslggniitaspisdlnpvfmasgtkltivsrgtrrtvpmdhtffpsyrktllgpeeill
sieipysredeffsafkqasrreddiakvtcgmrvlfqpgsmqvkelalcyggmadrtis
alkttqkqlskfwnekllqdvcaglaeelslspdapggmiefrrtltlsfffkfyltvlk
kl

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3eubL (L:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkfttlcvtgapgnckpwslrv

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubL (L:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkftt

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >3eubS (S:)
mtadelvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydr
lqdkiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgi
vmsmytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtfak

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubS (S:)
adelvffvngkkvveknadpettllaylrrklglrgtklgcgeggcgactvmlskydrlq
dkiihfsanaclapictlhhvavttvegigstktrlhpvqeriakshgsqcgfctpgivm
smytllrnqpeptveeiedafqgnlcrctgyrpilqgfrtf

  • Chain 'T':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3eubT (T:)
pkqlrfegervtwiqastlkelldlkaqhpeaklvvgnteigiemkfknqlfpmiicpaw
ipelnavehgpegisfgaacalssvektlleavaklptqktevfrgvleqlrwfagkqvk
svaslggniitaspisdlnpvfmasgtkltivsrgtrrtvpmdhtffpsyrktllgpeei
llsieipysredeffsafkqasrreddiakvtcgmrvlfqpgsmqvkelalcyggmadrt
isalkttqkqlskfwnekllqdvcaglaeelslspdapggmiefrrtltlsfffkfyltv
lkklg

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >3eubU (U:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkfttlcvtgapgnckpwslrv

    Sequence, based on observed residues (ATOM records): (download) 
    >3eubU (U:)
dtvgrplphlaaamqasgeavycddipryenelflrlvtstrahakiksidvseaqkvpg
fvcflsaddipgsnetglfndetvfakdtvtcvghiigavvadtpehaeraahvvkvtye
dlpaiitiedaiknnsfygselkiekgdlkkgfseadnvvsgelyiggqdhfylethcti
aipkgeegemelfvstqnamktqsfvakmlgvpvnrilvrvkrmgggfggketrstlvsv
avalaayktghpvrcmldrnedmlitggrhpflarykvgfmktgtivalevdhysnagns
rdlshsimeralfhmdncykipnirgtgrlcktnlssntafrgfggpqalfiaenwmsev
avtcglpaeevrwknmykegdlthfnqrlegfsvprcwdeclkssqyyarksevdkfnke
ncwkkrglciiptkfgisftvpflnqagalihvytdgsvlvshggtemgqglhtkmvqva
skalkipiskiyisetstntvpnssptaasvstdiygqavyeacqtilkrlepfkkknpd
gswedwvmaayqdrvslsttgfyrtpnlgysfetnsgnafhyftygvacseveidcltgd
hknlrtdivmdvgsslnpaidigqvegafvqglglftleelhyspegslhtrgpstykip
afgsiptefrvsllrdcpnkkaiyaskavgepplflgasvffaikdairaaraqhtnnnt
kelfrldspatpekirnacvdkftt