PDB entry 3erd

View 3erd on RCSB PDB site
Description: human estrogen receptor alpha ligand-binding domain in complex with diethylstilbestrol and a glucocorticoid receptor interacting protein 1 nr box II peptide
Class: nuclear receptor
Keywords: nuclear receptor, transcription factor, estrogen, agonist, coactivator
Deposited on 1999-03-31, released 1999-04-08
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.196
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (estrogen receptor alpha)
    Species: Homo sapiens [TaxId:9606]
    Gene: ESTROGEN RECEPTOR ALPHA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3erda_
  • Chain 'B':
    Compound: protein (estrogen receptor alpha)
    Species: Homo sapiens [TaxId:9606]
    Gene: ESTROGEN RECEPTOR ALPHA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3erdb_
  • Chain 'C':
    Compound: protein (glucocorticoid receptor interacting protein 1)
    Database cross-references and differences (RAF-indexed):
    • GB U39060 (Start-12)
  • Chain 'D':
    Compound: protein (glucocorticoid receptor interacting protein 1)
    Database cross-references and differences (RAF-indexed):
    • GB U39060 (0-End)
  • Heterogens: CL, DES, ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3erdA (A:)
mdpmikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladre
lvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrn
qgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekd
hihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknv
vplydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >3erdA (A:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahrlh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3erdB (B:)
mdpmikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladre
lvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrn
qgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekd
hihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknv
vplydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >3erdB (B:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfeekdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahrlh

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.