PDB entry 3erc

View 3erc on RCSB PDB site
Description: crystal structure of the heterodimeric vaccinia virus mrna polyadenylate polymerase with three fragments of rna and 3'-deoxy atp
Deposited on 2008-10-01, released 2009-06-16
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 3.21 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase
    Species: vaccinia virus WR [TaxId:10254]
    Gene: PAPS, VACWR095, F9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07617 (0-296)
      • engineered mutation (139)
      • engineered mutation (141-142)
  • Chain 'B':
    Compound: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase
    Species: vaccinia virus WR [TaxId:10254]
    Gene: PAPS, VACWR095, F9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07617 (0-296)
      • engineered mutation (139)
      • engineered mutation (141-142)
  • Chain 'C':
    Compound: Poly(A) polymerase catalytic subunit
    Species: vaccinia virus WR [TaxId:10254]
    Gene: PAPL, VACWR057, E1L
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23371 (0-478)
      • engineered mutation (35)
  • Chain 'D':
    Compound: Poly(A) polymerase catalytic subunit
    Species: vaccinia virus WR [TaxId:10254]
    Gene: PAPL, VACWR057, E1L
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23371 (0-478)
      • engineered mutation (35)
  • Chain 'E':
    Compound: RNA/DNA chimera (5'-D(CP*)R(UP*UP*)D(CP*C)-3')
  • Chain 'F':
    Compound: RNA/DNA chimera (5'-D(CP*)R(UP*UP*)D(CP*C)-3')
  • Chain 'G':
    Compound: RNA/DNA chimera (5'-D(CP*)R(UP*UP*)-D(C)-3')
  • Chain 'I':
    Compound: RNA/DNA chimera (5'-D(CP*CP*)R(UP*UP*)D(C)-3')
  • Heterogens: U, 3AT, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ercA (A:)
mdvvsldkpfmyfeeidneldyepesanevakklpyqgqlklllgelfflsklqrhgild
gatvvyigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeey
lrsikkqlhpskiilisdvasaaggnepstadllsnyalqnvmisilnpvasslkwrcpf
pdqwikdfyiphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyyln
kivrnkvvvnfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

    Sequence, based on observed residues (ATOM records):
    >3ercA (A:)
mdvvsldkpfmyfeeidneldyepesklpyqgqlklllgelfflsklqrhgildgatvvy
igsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeeylrsikk
qlhpskiilisdvasgnepstadllsnyalqnvmisilnpvasslkwrcpfpdqwikdfy
iphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyylnkivrnkvvv
nfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ercB (B:)
mdvvsldkpfmyfeeidneldyepesanevakklpyqgqlklllgelfflsklqrhgild
gatvvyigsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeey
lrsikkqlhpskiilisdvasaaggnepstadllsnyalqnvmisilnpvasslkwrcpf
pdqwikdfyiphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyyln
kivrnkvvvnfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

    Sequence, based on observed residues (ATOM records):
    >3ercB (B:)
mdvvsldkpfmyfeeidneldyepesklpyqgqlklllgelfflsklqrhgildgatvvy
igsapgthirylrdhfynlgviikwmlidgrhhdpilnglrdvtlvtrfvdeeylrsikk
qlhpskiilisdvasgnepstadllsnyalqnvmisilnpvasslkwrcpfpdqwikdfy
iphgnkmlqpfapsysaemrllsiytgenmrltrvtksdavnyekkmyylnkivrnkvvv
nfdypnqeydyfhmyfmlrtvycnktfpttkakvlflqqsifrflnip

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3ercC (C:)
mnrnpdqntlpnitlkiietylgrvpsvneyhmlksqarniqkitvfnkdifvslvkknk
krffsdvntsaseikdrilsyfskqtqtynigklftiielqsvlvttytdilgvltikap
nvisskisynvtsmeelardmlnsmnvavidkakvmgrhnvsslvknvnklmeeylrrhn
kscicygsyslylinpnirygdidilqtnsrtflidlaflikfitgnniilskipylrny
mvikdendnhiidsfnirqdtmnvvpkifidniyivdptfqllnmikmfsqidrledlsk
dpekfnarmatmleyvrythgivfdgkrnnmpmkciidennrivtvttkdyfsfkkclvy
ldenvlssdildlnadtscdfesvtnsvylihdnimytyfsntillsdkgkvheisargl
cahillyqmltsgeykqclsdllnsmmnrdkipiyshterdkkpgrhgfiniekdiivf

    Sequence, based on observed residues (ATOM records):
    >3ercC (C:)
nitlkiietylgrvpsvneyhmlksqarniqkitvfnkdifvslvkknkkrffsdvntsa
seikdrilsyfskqtqtynigklftiielqsvlvttytdilgvltinvtsmeelardmln
smnvavvsslvknvnklmeeylrrhnkscicygsyslylinpnirygdidilqtnsrtfl
idlaflikfitgnniilskipylrnymvikdendnhiidsfnirqdtmnvvpkifidniy
ivdptfqllnmikmfsqidrledlskdpekfnarmatmleyvrythgivfdgkrnnmpmk
ciidennrivtvttkdyfsfkkclvyldenvlssdildlnadtscdfesvtnsvylihdn
imytyfsntillsdkgkvheisarglcahillyqmltsgeykqclsdllnsmmnrdkipi
yshterdkkpgrhgfiniekdiivf

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3ercD (D:)
mnrnpdqntlpnitlkiietylgrvpsvneyhmlksqarniqkitvfnkdifvslvkknk
krffsdvntsaseikdrilsyfskqtqtynigklftiielqsvlvttytdilgvltikap
nvisskisynvtsmeelardmlnsmnvavidkakvmgrhnvsslvknvnklmeeylrrhn
kscicygsyslylinpnirygdidilqtnsrtflidlaflikfitgnniilskipylrny
mvikdendnhiidsfnirqdtmnvvpkifidniyivdptfqllnmikmfsqidrledlsk
dpekfnarmatmleyvrythgivfdgkrnnmpmkciidennrivtvttkdyfsfkkclvy
ldenvlssdildlnadtscdfesvtnsvylihdnimytyfsntillsdkgkvheisargl
cahillyqmltsgeykqclsdllnsmmnrdkipiyshterdkkpgrhgfiniekdiivf

    Sequence, based on observed residues (ATOM records):
    >3ercD (D:)
nitlkiietylgrvpsvneyhmlksqarniqkitvfnkdifvslvkknkkrffsdvntsa
seikdrilsyfskqtqtynigklftiielqsvlvttytdilgvltinvtsmeelardmln
smnvavvsslvknvnklmeeylrrhnkscicygsyslylinpnirygdidilqtnsrtfl
idlaflikfitgnniilskipylrnymvikdendnhiidsfnirqdtmnvvpkifidniy
ivdptfqllnmikmfsqidrledlskdpekfnarmatmleyvrythgivfdgkrnnmpmk
ciidennrivtvttkdyfsfkkclvyldenvlssdildlnadtscdfesvtnsvylihdn
imytyfsntillsdkgkvheisarglcahillyqmltsgeykqclsdllnsmmnrdkipi
yshterdkkpgrhgfiniekdiivf

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'I':
    No sequence available.