PDB entry 3eqy

View 3eqy on RCSB PDB site
Description: crystal structure of human mdmx in complex with a 12-mer peptide inhibitor
Deposited on 2008-10-01, released 2009-03-17
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: 0.156
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mdm4 protein
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15151 (0-84)
      • engineered mutation (44-46)
  • Chain 'B':
    Compound: mdm4 protein
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15151 (0-84)
      • engineered mutation (44-46)
  • Chain 'C':
    Compound: 12-mer peptide inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EQY (0-11)
  • Chain 'D':
    Compound: 12-mer peptide inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EQY (0-11)
  • Heterogens: GAI, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3eqyA (A:)
inqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydaaaqhmvycggdllge
llgrqsfsvkdpsplydmlrknlvt

    Sequence, based on observed residues (ATOM records):
    >3eqyA (A:)
nqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydaaaqhmvycggdllgel
lgrqsfsvkdpsplydmlrknlvt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3eqyB (B:)
inqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydaaaqhmvycggdllge
llgrqsfsvkdpsplydmlrknlvt

    Sequence, based on observed residues (ATOM records):
    >3eqyB (B:)
nqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydaaaqhmvycggdllgel
lgrqsfsvkdpsplydmlrknlvt

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >3eqyC (C:)
tsfaeywnllsp

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >3eqyD (D:)
tsfaeywnllsp