PDB entry 3eqr

View 3eqr on RCSB PDB site
Description: Crystal Structure of Ack1 with compound T74
Class: Transferase
Keywords: ack1, Alternative splicing, ATP-binding, Cell membrane, Kinase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, SH3 domain, Transferase, Tyrosine-protein kinase
Deposited on 2008-10-01, released 2008-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-06-02, with a file datestamp of 2009-05-29.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.212
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Activated CDC42 kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNK2, ACK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3eqra_
  • Chain 'B':
    Compound: Activated CDC42 kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNK2, ACK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3eqrb_
  • Heterogens: T74, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eqrA (A:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfaw
capeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedc
pqdiynvmvqcwahkpedrptfvalrdflleaqptd

    Sequence, based on observed residues (ATOM records): (download) 
    >3eqrA (A:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpeamddfirevnamh
sldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqvaegmgy
leskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfawcapesl
ktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqdiyn
vmvqcwahkpedrptfvalrdflleaqptd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3eqrB (B:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfaw
capeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedc
pqdiynvmvqcwahkpedrptfvalrdflleaqptd

    Sequence, based on observed residues (ATOM records): (download) 
    >3eqrB (B:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmrkvpfawcap
eslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqd
iynvmvqcwahkpedrptfvalrdflleaqp