PDB entry 3eqp

View 3eqp on RCSB PDB site
Description: Crystal Structure of Ack1 with compound T95
Class: Transferase
Keywords: ack1, Alternative splicing, ATP-binding, Cell membrane, Kinase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, SH3 domain, Transferase, Tyrosine-protein kinase
Deposited on 2008-10-01, released 2008-12-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-06-02, with a file datestamp of 2009-05-29.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.224
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Activated CDC42 kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNK2, ACK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3eqpa_
  • Chain 'B':
    Compound: Activated CDC42 kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TNK2, ACK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3eqpb_
  • Heterogens: T95, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eqpA (A:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfaw
capeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedc
pqdiynvmvqcwahkpedrptfvalrdflleaqptd

    Sequence, based on observed residues (ATOM records): (download) 
    >3eqpA (A:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclqpeamddfirevnamh
sldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqvaegmgy
leskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfawcapesl
ktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqdiyn
vmvqcwahkpedrptfvalrdflleaqp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3eqpB (B:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclkpdvlsqpeamddfir
evnamhsldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqv
aegmgyleskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfaw
capeslktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedc
pqdiynvmvqcwahkpedrptfvalrdflleaqptd

    Sequence, based on observed residues (ATOM records): (download) 
    >3eqpB (B:)
ltcligekdlrlleklgdgsfgvvrrgewdapsgktvsvavkclqpeamddfirevnamh
sldhrnlirlygvvltppmkmvtelaplgslldrlrkhqghfllgtlsryavqvaegmgy
leskrfihrdlaarnlllatrdlvkigdfglmralpqnddhyvmqehrkvpfawcapesl
ktrtfshasdtwmfgvtlwemftygqepwiglngsqilhkidkegerlprpedcpqdiyn
vmvqcwahkpedrptfvalrdflleaqptd