PDB entry 3ep8

View 3ep8 on RCSB PDB site
Description: human adometdc e178q mutant complexed with s-adenosylmethionine methyl ester and no putrescine bound
Deposited on 2008-09-29, released 2008-12-23
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: s-adenosylmethionine decarboxylase alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: AMD1, AMD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17707 (0-259)
      • engineered mutation (109)
  • Chain 'B':
    Compound: s-adenosylmethionine decarboxylase beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: AMD1, AMD
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PYR, SMM, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ep8A (A:)
smfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyphr
nfqeeieflnaifpngaaycmgrmnsdcwylytldfpesrvisqpdqtlqilmseldpav
mdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpep
efsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspqkiegfkrl
dcqsamfndynfvftsfakk

    Sequence, based on observed residues (ATOM records):
    >3ep8A (A:)
smfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyphr
nfqeeieflnaifpngaaycmgrmnsdcwylytldfpdqtlqilmseldpavmdqfymkd
gvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpepefsyvsfe
tnlsqtsyddlirkvvevfkpgkfvttlfvnqkiegfkrldcqsamfndynfvftsfakk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ep8B (B:)
meaahffegtekllevwfsrqqpdanqgsgdlrtiprsewdillkdvqcsiisvtktdkq
eayvlse

    Sequence, based on observed residues (ATOM records):
    >3ep8B (B:)
ahffegtekllevwfsqgsgdlrtiprsewdillkdvqcsiisvtktdkqeayvlse