PDB entry 3eo3

View 3eo3 on RCSB PDB site
Description: crystal structure of the n-acetylmannosamine kinase domain of human gne protein
Deposited on 2008-09-26, released 2008-10-07
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.84 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GNE, GLCNE
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GNE, GLCNE
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: GNE, GLCNE
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, UNX

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3eo3A (A:)
mhhhhhhssgrenlyfqgtlsalavdlggtnlrvaivsmkgeivkkytqfnpktyeerin
lilqmcveaaaeavklncrilgvgistggrvnpregivlhstkliqewnsvdlrtplsdt
lhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgigggiihqhelihgssfcaael
ghlvvsldgpdcscgshgcieayasgmalqreakklhdedlllvegmsvpkdeavgalhl
iqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsgvlashyihivkdvirqqa
lssvqdvdvvvsdlvdpallgaasmvldyttrr

    Sequence, based on observed residues (ATOM records):
    >3eo3A (A:)
tlsalavdlggtnlrvaivsmkgeivkkytqfnpktyeerinlilqmcveaaaeavklnc
rilgvgistdlrtplsdtlhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgiggg
iihqhelihgssfcaaelghlvvsldgpdcscgshgcieayasgmalqreakklhdedll
lvegmsvpkdeavgalhliqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsg
vlashyihivkdvirqqalssvqdvdvvvsdlvdpallgaasmvldyt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3eo3B (B:)
mhhhhhhssgrenlyfqgtlsalavdlggtnlrvaivsmkgeivkkytqfnpktyeerin
lilqmcveaaaeavklncrilgvgistggrvnpregivlhstkliqewnsvdlrtplsdt
lhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgigggiihqhelihgssfcaael
ghlvvsldgpdcscgshgcieayasgmalqreakklhdedlllvegmsvpkdeavgalhl
iqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsgvlashyihivkdvirqqa
lssvqdvdvvvsdlvdpallgaasmvldyttrr

    Sequence, based on observed residues (ATOM records):
    >3eo3B (B:)
tlsalavdlggtnlrvaivsmkgeivkkytqfnpktyeerinlilqmcveaaaeavklnc
rilgvgistdlrtplsdtlhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgiggg
iihqhelihgssfcaaelghlvvsldgpdcscgshgcieayasgmalqreakklhdedll
lvegmsavgalhliqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsgvlash
yihivkdvirqqalssvqdvdvvvsdlvdpallgaasmvldyt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3eo3C (C:)
mhhhhhhssgrenlyfqgtlsalavdlggtnlrvaivsmkgeivkkytqfnpktyeerin
lilqmcveaaaeavklncrilgvgistggrvnpregivlhstkliqewnsvdlrtplsdt
lhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgigggiihqhelihgssfcaael
ghlvvsldgpdcscgshgcieayasgmalqreakklhdedlllvegmsvpkdeavgalhl
iqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsgvlashyihivkdvirqqa
lssvqdvdvvvsdlvdpallgaasmvldyttrr

    Sequence, based on observed residues (ATOM records):
    >3eo3C (C:)
tlsalavdlgtnlrvaivsmkgeivkkytqfnpktyeerinlilqmcveaaaeavklncr
ilgvgistdlrtplsdtlhlpvwvdndgncaalaerkfgqgkglenfvtlitgtgigggi
ihqhelihgssfcaaelghlvvsldgpdcscgshgcieayasgmalqreakklhdedlll
vegmsvpkeavgalhliqaaklgnakaqsilrtagtalglgvvnilhtmnpslvilsgvl
ashyihivkdvirqqalssvqdvdvvvsdlvdpallgaasmvldyt