PDB entry 3ejt

View 3ejt on RCSB PDB site
Description: Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog:(5R)-5-[2'-(4-tert-butylphenyl)ethyl]-swainsonine
Class: hydrolase
Keywords: GH38 Glycosidase, Glycosidase, Golgi apparatus, Hydrolase, Membrane, Metal-binding, Signal-anchor, Transmembrane
Deposited on 2008-09-18, released 2009-10-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.35 Å
R-factor: 0.158
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-mannosidase 2
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alpha-Man-II, GmII
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q24451 (Start-1044)
      • see remark 999 (906)
    Domains in SCOPe 2.06: d3ejta1, d3ejta2, d3ejta3
  • Heterogens: NAG, ZN, MRD, DMS, HN6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ejtA (A:)
rsshhhhhhgefddpirpplkvarsprpgqcqdvvqdvpnvdvqmlelydrmsfkdidgg
vwkqgwnikydplkynahhklkvfvvphshndpgwiqtfeeyyqhdtkhilsnalrhlhd
npemkfiwaeisyfarfyhdlgenkklqmksivkngqlefvtggwvmpdeanshwrnvll
qltegqtwlkqfmnvtptaswaidpfghsptmpyilqksgfknmliqrthysvkkelaqq
rqleflwrqiwdnkgdtalfthmmpfysydiphtcgpdpkvccqfdfkrmgsfglscpwk
vpprtisdqnvaarsdllvdqwkkkaelyrtnvlliplgddfrfkqntewdvqrvnyerl
fehinsqahfnvqaqfgtlqeyfdavhqaeragqaefptlsgdfftyadrsdnywsgyyt
srpyhkrmdrvlmhyvraaemlsawhswdgmarieerleqarrelslfqhhdgitgtakt
hvvvdyeqrmqealkacqmvmqqsvyrlltkpsiyspdfsfsyftlddsrwpgsgvedsr
ttiilgedilpskhvvmhntlphwreqlvdfyvsspfvsvtdlannpveaqvspvwswhh
dtltktihpqgsttkyriifkarvppmglatyvltisdskpehtsyasnlllrknptslp
lgqypedvkfgdpreislrvgngptlafseqgllksiqltqdsphvpvhfkflkygvrsh
gdrsgaylflpngpaspvelgqpvvlvtkgklessvsvglpsvvhqtimrggapeirnlv
digsldnteivmrlethidsgdifytdlnglqfikrrrldklplqanyypipsgmfieda
ntrltlltgqplggsslasgeleimqdrrlasdderglgqgvldnkpvlhiyrlvlekvn
ncvrpsklhpagyltsaahkasqslldpldkfifaenewigaqgqfggdhpsaredldvs
vmrrltkssaktqrvgyvlhrtnlmqcgtpeehtqkldvchllpnvarcerttltflqnl
ehldgmvapevcpmetaayvsshss

    Sequence, based on observed residues (ATOM records): (download) 
    >3ejtA (A:)
qcqdvvqdvpnvdvqmlelydrmsfkdidggvwkqgwnikydplkynahhklkvfvvphs
hndpgwiqtfeeyyqhdtkhilsnalrhlhdnpemkfiwaeisyfarfyhdlgenkklqm
ksivkngqlefvtggwvmpdeanshwrnvllqltegqtwlkqfmnvtptaswaidpfghs
ptmpyilqksgfknmliqrthysvkkelaqqrqleflwrqiwdnkgdtalfthmmpfysy
diphtcgpdpkvccqfdfkrmgsfglscpwkvpprtisdqnvaarsdllvdqwkkkaely
rtnvlliplgddfrfkqntewdvqrvnyerlfehinsqahfnvqaqfgtlqeyfdavhqa
eragqaefptlsgdfftyadrsdnywsgyytsrpyhkrmdrvlmhyvraaemlsawhswd
gmarieerleqarrelslfqhhdgitgtakthvvvdyeqrmqealkacqmvmqqsvyrll
tkpsiyspdfsfsyftlddsrwpgsgvedsrttiilgedilpskhvvmhntlphwreqlv
dfyvsspfvsvtdlannpveaqvspvwswhhdtltktihpqgsttkyriifkarvppmgl
atyvltisdskpehtsyasnlllrknptslplgqypedvkfgdpreislrvgngptlafs
eqgllksiqltqdsphvpvhfkflkygvrshgdrsgaylflpngpaspvelgqpvvlvtk
gklessvsvglpsvvhqtimrggapeirnlvdigsldnteivmrlethidsgdifytdln
glqfikrrrldklplqanyypipsgmfiedantrltlltgqplggsslasgeleimqdrr
lasdderglgqgvldnkpvlhiyrlvlekvnncvrpsklhpagyltsaahkasqslldpl
dkfifaenewigaqgqfggdhpsaredldvsvmrrltkssaktqrvgyvlhrtnlmqcgt
peehtqkldvchllpnvarcerttltflqnlehldgmvapevcpmetaayvsshss