PDB entry 3ejq

View 3ejq on RCSB PDB site
Description: Golgi alpha-Mannosidase II in complex with 5-substitued swainsonine analog: (5R)-5-[2'-oxo-2'-(4-methylphenyl)ethyl]-swainsonine
Class: hydrolase
Keywords: GH38 Glycosidase, Glycosidase, Golgi apparatus, Hydrolase, Membrane, Metal-binding, Signal-anchor, Transmembrane
Deposited on 2008-09-18, released 2009-10-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-mannosidase 2
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alpha-Man-II, GmII
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q24451 (Start-1044)
      • see remark 999 (906)
    Domains in SCOPe 2.08: d3ejqa1, d3ejqa2, d3ejqa3
  • Heterogens: NAG, ZN, MRD, HN3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ejqA (A:)
rsshhhhhhgefddpirpplkvarsprpgqcqdvvqdvpnvdvqmlelydrmsfkdidgg
vwkqgwnikydplkynahhklkvfvvphshndpgwiqtfeeyyqhdtkhilsnalrhlhd
npemkfiwaeisyfarfyhdlgenkklqmksivkngqlefvtggwvmpdeanshwrnvll
qltegqtwlkqfmnvtptaswaidpfghsptmpyilqksgfknmliqrthysvkkelaqq
rqleflwrqiwdnkgdtalfthmmpfysydiphtcgpdpkvccqfdfkrmgsfglscpwk
vpprtisdqnvaarsdllvdqwkkkaelyrtnvlliplgddfrfkqntewdvqrvnyerl
fehinsqahfnvqaqfgtlqeyfdavhqaeragqaefptlsgdfftyadrsdnywsgyyt
srpyhkrmdrvlmhyvraaemlsawhswdgmarieerleqarrelslfqhhdgitgtakt
hvvvdyeqrmqealkacqmvmqqsvyrlltkpsiyspdfsfsyftlddsrwpgsgvedsr
ttiilgedilpskhvvmhntlphwreqlvdfyvsspfvsvtdlannpveaqvspvwswhh
dtltktihpqgsttkyriifkarvppmglatyvltisdskpehtsyasnlllrknptslp
lgqypedvkfgdpreislrvgngptlafseqgllksiqltqdsphvpvhfkflkygvrsh
gdrsgaylflpngpaspvelgqpvvlvtkgklessvsvglpsvvhqtimrggapeirnlv
digsldnteivmrlethidsgdifytdlnglqfikrrrldklplqanyypipsgmfieda
ntrltlltgqplggsslasgeleimqdrrlasdderglgqgvldnkpvlhiyrlvlekvn
ncvrpsklhpagyltsaahkasqslldpldkfifaenewigaqgqfggdhpsaredldvs
vmrrltkssaktqrvgyvlhrtnlmqcgtpeehtqkldvchllpnvarcerttltflqnl
ehldgmvapevcpmetaayvsshss

    Sequence, based on observed residues (ATOM records): (download) 
    >3ejqA (A:)
qcqdvvqdvpnvdvqmlelydrmsfkdidggvwkqgwnikydplkynahhklkvfvvphs
hndpgwiqtfeeyyqhdtkhilsnalrhlhdnpemkfiwaeisyfarfyhdlgenkklqm
ksivkngqlefvtggwvmpdeanshwrnvllqltegqtwlkqfmnvtptaswaidpfghs
ptmpyilqksgfknmliqrthysvkkelaqqrqleflwrqiwdnkgdtalfthmmpfysy
diphtcgpdpkvccqfdfkrmgsfglscpwkvpprtisdqnvaarsdllvdqwkkkaely
rtnvlliplgddfrfkqntewdvqrvnyerlfehinsqahfnvqaqfgtlqeyfdavhqa
eragqaefptlsgdfftyadrsdnywsgyytsrpyhkrmdrvlmhyvraaemlsawhswd
gmarieerleqarrelslfqhhdgitgtakthvvvdyeqrmqealkacqmvmqqsvyrll
tkpsiyspdfsfsyftlddsrwpgsgvedsrttiilgedilpskhvvmhntlphwreqlv
dfyvsspfvsvtdlannpveaqvspvwswhhdtltktihpqgsttkyriifkarvppmgl
atyvltisdskpehtsyasnlllrknptslplgqypedvkfgdpreislrvgngptlafs
eqgllksiqltqdsphvpvhfkflkygvrshgdrsgaylflpngpaspvelgqpvvlvtk
gklessvsvglpsvvhqtimrggapeirnlvdigsldnteivmrlethidsgdifytdln
glqfikrrrldklplqanyypipsgmfiedantrltlltgqplggsslasgeleimqdrr
lasdderglgqgvldnkpvlhiyrlvlekvnncvrpsklhpagyltsaahkasqslldpl
dkfifaenewigaqgqfggdhpsaredldvsvmrrltkssaktqrvgyvlhrtnlmqcgt
peehtqkldvchllpnvarcerttltflqnlehldgmvapevcpmetaayvsshss