PDB entry 3ehx
View 3ehx on RCSB PDB site
Description: Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor (R)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acid
Class: hydrolase
Keywords: MATRIX METALLOPROTEINASE, MMP12, ELASTASE, COMPLEX (ELASTASE/INHIBITOR), METALLO ELASTASE,, Calcium, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Secreted, Zinc, Zymogen
Deposited on
2008-09-15, released
2009-05-19
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-05-19, with a file datestamp of
2009-05-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.166
AEROSPACI score: 0.51
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d3ehxa_ - Heterogens: ZN, CA, BDL, HOH