PDB entry 3eht

View 3eht on RCSB PDB site
Description: crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (crfr1) in complex with crf
Deposited on 2008-09-14, released 2008-09-30
The last revision was dated 2021-10-20, with a file datestamp of 2021-10-15.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fusion protein of CRFR1 extracellular domain and MBP
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AEX9 (1-367)
      • initiating methionine (0)
      • engineered mutation (93)
      • linker (368-373)
      • expression tag (470-475)
    • Uniprot P34998 (374-469)
      • amidation (392)
  • Chain 'B':
    Compound: Corticoliberin
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3ehtA (A:)
makieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpd
iifwahdrfggyaqsgllaeitpdkafqdklypetwdavryngkliaypiavealsliyn
kdllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydi
kdvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidts
kvnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkp
lgavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvd
ealkdaqtnaaaefslqdqhceslslasnisglqcnasvdligtcwprspagqlvvrpcp
affygvrynttnngyreclangswaarvnysecqeilneekkskvhyhvahhhhhh

    Sequence, based on observed residues (ATOM records):
    >3ehtA (A:)
kieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdii
fwahdrfggyaqsgllaeitpdkafqdklypetwdavryngkliaypiavealsliynkd
llpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikd
vgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskv
nygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplg
avalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdea
lkdaqtnaaaefslqdqhceslslasnisglqcnasvdligtcwprspagqlvvrpcpaf
fygvrynttnngyreclangswaarvnysecq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3ehtB (B:)
laqqahsnrklmeii

    Sequence, based on observed residues (ATOM records):
    >3ehtB (B:)
ahsnrklmeii