PDB entry 3egs

View 3egs on RCSB PDB site
Description: crystal structure of the hiv-1 broadly neutralizing antibody 2f5 in complex with the gp41 scrambledfp-mper scrhyb3k construct gigafgllgflaagskk-ahx-k656neqelleldkwaslwn671 soaked in ammonium sulfate
Deposited on 2008-09-11, released 2009-08-25
The last revision was dated 2010-01-12, with a file datestamp of 2010-01-08.
Experiment type: XRAY
Resolution: 3.6 Å
R-factor: 0.235
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2F5 Fab' light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EGS (0-End)
  • Chain 'B':
    Compound: 2F5 Fab' heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EGS (0-End)
  • Chain 'C':
    Compound: gp41 scrFP-MPER construct
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EGS

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3egsA (A:)
    alqltqspsslsasvgdrititcrasqgvtsalawyrqkpgsppqlliydasslesgvps
    rfsgsgsgteftltistlrpedfatyycqqlhfyphtfgggtrvdvrrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyecevthqglsspvtksfnrgec
    

    Sequence, based on observed residues (ATOM records):
    >3egsA (A:)
    alqltqspsslsasvgdrititcrasqgvtsalawyrqkpgsppqlliydasslesgvps
    rfsgsgsgteftltistlrpedfatyycqqlhfyphtfgggtrvdvrrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyecevthqglsspvtksfnrge
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3egsB (B:)
    ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
    yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgpttlfgvpiargpvnamd
    vwgqgitvtisststkgpsvfplapsskstaggtaalgclvkdyfpepvtvswnsgalts
    gvhtfpavlqssglyslssvvtvpssslgtqtytcnvnhkpsntkvdkrvepksc
    

    Sequence, based on observed residues (ATOM records):
    >3egsB (B:)
    ritlkesgpplvkptqtltltcsfsgfslsdfgvgvgwirqppgkalewlaiiysdddkr
    yspslntrltitkdtsknqvvlvmtrvspvdtatyfcahrrgptgpvnamdvwgqgitvt
    isststkgpsvfplapgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
    lssvvtvpssslgtqtytcnvnhkpsntkvdkrvep
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3egsC (C:)
    gigafgllgflaagskkxkneqelleldkwaslwn
    

    Sequence, based on observed residues (ATOM records):
    >3egsC (C:)
    eldkwas