PDB entry 3egh

View 3egh on RCSB PDB site
Description: crystal structure of a complex between protein phosphatase 1 alpha (pp1), the pp1 binding and pdz domains of spinophilin and the small natural molecular toxin nodularin-r
Deposited on 2008-09-10, released 2010-03-23
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1CA, PPP1A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1CA, PPP1A
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Spinophilin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ppp1r9b
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Spinophilin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ppp1r9b
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: nodularin R
    Species: Nodularia spumigena, synthetic [TaxId:70799]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00279 (0-4)
  • Chain 'F':
    Compound: nodularin R
    Species: Nodularia spumigena, synthetic [TaxId:70799]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00279 (0-4)
  • Heterogens: GOL, MN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3eghA (A:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpadk
nkgkygqfsglnpggrpitpprnsakakk

    Sequence, based on observed residues (ATOM records):
    >3eghA (A:)
lnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3eghB (B:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpadk
nkgkygqfsglnpggrpitpprnsakakk

    Sequence, based on observed residues (ATOM records):
    >3eghB (B:)
lnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3eghC (C:)
gsmdeedgeppyepesgcveipglseeedpapsrkihfstapiqvfstysnedydrrned
vdpmaasaeyelekrverlelfpvelekdseglgisiigmgagadmgleklgifvktvte
ggaahrdgriqvndllvevdgtslvgvtqsfaasvlrntkgrvrfmigre

    Sequence, based on observed residues (ATOM records):
    >3eghC (C:)
pyepesgcveipglseeedpapsrkihfstapiqvfstysnedydrrnedvdpmaasaey
elekrverlelfpvelekdseglgisiigmgagadmgleklgifvktvteggaahrdgri
qvndllvevdgtslvgvtqsfaasvlrntkgrvrfmigre

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3eghD (D:)
gsmdeedgeppyepesgcveipglseeedpapsrkihfstapiqvfstysnedydrrned
vdpmaasaeyelekrverlelfpvelekdseglgisiigmgagadmgleklgifvktvte
ggaahrdgriqvndllvevdgtslvgvtqsfaasvlrntkgrvrfmigre

    Sequence, based on observed residues (ATOM records):
    >3eghD (D:)
pyepesgcveipglseeedpapsrkihfstapiqvfstysnedydrrnedvdpmaasaey
elekrv

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >3eghE (E:)
drxxx

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >3eghF (F:)
drxxx