PDB entry 3egg

View 3egg on RCSB PDB site
Description: Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Spinophilin
Class: hydrolase
Keywords: PP1, Spinophilin, Serine/Threonine Phosphatase, Post Synaptic Density, Glutametergic Receptors, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Hydrolase, Iron, Manganese, Metal-binding, Phosphoprotein, Protein phosphatase, Actin-binding, Cell junction, Cell projection, Cytoskeleton, Developmental protein, Differentiation, Neurogenesis, Nucleus, Synapse
Deposited on 2008-09-10, released 2010-03-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.181
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1CA, PPP1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3egga_
  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP1CA, PPP1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d3eggb_
  • Chain 'C':
    Compound: Spinophilin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ppp1r9b
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Spinophilin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Ppp1r9b
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, MN, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3eggA (A:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpadk
nkgkygqfsglnpggrpitpprnsakakk

    Sequence, based on observed residues (ATOM records): (download) 
    >3eggA (A:)
lnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3eggB (B:)
ghmgslnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplki
cgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffll
rgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlq
smeqirrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdl
dlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpadk
nkgkygqfsglnpggrpitpprnsakakk

    Sequence, based on observed residues (ATOM records): (download) 
    >3eggB (B:)
lnldsiigrllevqgsrpgknvqlteneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvqgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpad

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.