PDB entry 3egd

View 3egd on RCSB PDB site
Description: Crystal structure of the mammalian COPII-coat protein Sec23a/24a complexed with the SNARE protein Sec22 and bound to the transport signal sequence of vesicular stomatitis virus glycoprotein
Deposited on 2008-09-10, released 2008-10-21
The last revision was dated 2014-04-16, with a file datestamp of 2014-04-11.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.206
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein transport protein Sec23A
    Species: Homo sapiens [TaxId:9606]
    Gene: SEC23A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Protein transport protein Sec24A
    Species: Homo sapiens [TaxId:9606]
    Gene: SEC24A
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95486 (0-747)
      • conflict (710)
  • Chain 'C':
    Compound: Vesicle-trafficking protein SEC22b
    Species: Homo sapiens [TaxId:9606]
    Gene: SEC22B, SEC22L1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 10 residue peptide from VSV glycoprotein
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EGD (Start-9)
  • Heterogens: ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3egdA (A:)
mttylefiqqneerdgvrfswnvwpssrleatrmvvpvaalftplkerpdlppiqyepvl
csrttcravlnplcqvdyraklwacnfcyqrnqfppsyagiselnqpaellpqfssieyv
vlrgpqmpliflyvvdtcmededlqalkesmqmslsllpptalvglitfgrmvqvhelgc
egisksyvfrgtkdlsakqlqemlglskvpltqatrgpqvqqpppsnrflqpvqkidmnl
tdllgelqrdpwpvpqgkrplrssgvalsiavgllectfpntgarimmfiggpatqgpgm
vvgdelktpirswhdidkdnakyvkkgtkhfealanraattghvidiyacaldqtgllem
kccpnltggymvmgdsfntslfkqtfqrvftkdmhgqfkmgfggtleiktsreikisgai
gpcvslnskgpcvseneigtggtcqwkicglsptttlaiyfevvnqhnapipqggrgaiq
fvtqyqhssgqrrirvttiarnwadaqtqiqniaasfdqeaaailmarlaiyraeteegp
dvlrwldrqlirlcqkfgeyhkddpssfrfsetfslypqfmfhlrrssflqvfnnspdes
syyrhhfmrqdltqslimiqpilyaysfsgppepvlldsssiladrillmdtffqiliyh
getiaqwrksgyqdmpeyenfrhllqapvddaqeilhsrfpmpryidtehggsqarflls
kvnpsqthnnmyawgqesgapiltddvslqvfmdhlkklavssa

    Sequence, based on observed residues (ATOM records):
    >3egdA (A:)
tylefiqqneerdgvrfswnvwpssrleatrmvvpvaalftplkerpdlppiqyepvlcs
rttcravlnplcqvdyraklwacnfcyqrnqfppsyagiselnqpaellpqfssieyvvl
rgpqmpliflyvvdtcmededlqalkesmqmslsllpptalvglitfgrmvqvhelgceg
isksyvfrgtkdlsakqlqemlgpppsnrflqpvqkidmnltdllgelqrdpwpvpqgkr
plrssgvalsiavgllectfpntgarimmfiggpatqgpgmvvgdelktpirswhdidkd
nakyvkkgtkhfealanraattghvidiyacaldqtgllemkccpnltggymvmgdsfnt
slfkqtfqrvftkdmhgqfkmgfggtleiktsreikisgaigpcvslnskgpcvseneig
tggtcqwkicglsptttlaiyfevvggrgaiqfvtqyqhssgqrrirvttiarnwadaqt
qiqniaasfdqeaaailmarlaiyraetedvlrwldrqlirlcqkfgeyhkddpssfrfs
etfslypqfmfhlrrssflqvfnnspdessyyrhhfmrqdltqslimiqpilyaysfsgp
pepvlldsssiladrillmdtffqiliyhgetiaqwrksgyqdmpeyenfrhllqapvdd
aqeilhsrfpmpryidtehggsqarfllskvndvslqvfmdhlkklavssa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3egdB (B:)
eglrvvnllqernmlpstplkppvpnlhediqklncnpelfrctltsipqtqallnkakl
plglllhpfkdlvqlpvvtsstivrcrscrtyinpfvsfldqrrwkcnlcyrvndvpeef
lynpltrvygephrrpevqnatiefmapseymlrppqppvylfvfdvshnavetgylnsv
cqslldnldllpgntrtkigfitfdstihfyglqeslsqpqmlivsdiedvfipmpenll
vnlneskelvqdllktlpqmftktletqsalgpalqaafklmsptggrmsvfqtqlptlg
vgalkpreepnhrssakdihmtpstdfykklaldcsgqqvavdlfllsgqysdlaslgci
srysagsvyyypsyhhqhnpvqvqklqkelqryltrkigfeavmrirctkglsihtfhgn
ffvrstdllslpnvnpdagyavqmsveesltdtqlvsfqsallytsskgerrirvhtlcl
pvvstlndvflgadvqaisgllanmavdrsmtaslsdardalvnavidslsayrssvlsn
qqpglmvpfslrlfplfvlallkqksfqtgtnarlderifamcqvknqplvylmltthps
lyrvdnlsdegalnisdrtipqppilqlsveklsrdgaflmdagsvlmlwvgknctqnfl
sqvlgvqnyasipqpmtdlpeldtpesariiafiswlreqrpffpilyviadespmkanf
lqnmiedrtesalsyyefllhiqqqvnk

    Sequence, based on observed residues (ATOM records):
    >3egdB (B:)
eglrvvnllqernmlpstplkppvpnlhediqklncnpelfrctltsipqtqallnkakl
plglllhpfkdlvqlpvvtsstivrcrscrtyinpfvsfldqrrwkcnlcyrvndvpeef
lephrrpevqnatiefmapseymlrppqppvylfvfdvshnavetgylnsvcqslldnld
llpgntrtkigfitfdstihfyglqeslsqpqmlivsdiedvfipmpenllvnlneskel
vqdllktlpqmftktletqsalgpalqaafklmsptggrmsvfqtqlptlgvgalkpree
pnhrssakmtpstdfykklaldcsgqqvavdlfllsgqysdlaslgcisrysagsvyyyp
syhhqhnpvqvqklqkelqryltrkigfeavmrirctkglsihtfhgnffvrstdllslp
nvnpdagyavqmsveesltdtqlvsfqsallytsskgerrirvhtlclpvvstlndvflg
advqaisgllanmavdrsmtaslsdardalvnavidslsayrssvpglmvpfslrlfplf
vlallkqksfqtgtnarlderifamcqvknqplvylmltthpslyrvdnlsdegalnisd
rtipqppilqlsveklsrdgaflmdagsvlmlwvgknctqnflsqvlgvqnyasipqpmt
dlpeldtpesariiafiswlreqrpffpilyviadespmkanflqnmiedrtesalsyye
fllhiqqqvnk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3egdC (C:)
mvlltmiarvadglplaasmqedeqsgrdlqqyqsqakqlfrklneqsptrctleagamt
fhyiieqgvcylvlceaafpkklafayledlhsefdeqhgkkvptvsrpysfiefdtfiq
ktkklyidsrarrnlgsintelqdvqrimvanieevl

    Sequence, based on observed residues (ATOM records):
    >3egdC (C:)
mvlltmiarvadglplaasmqeddlqqyqsqakqlfrklneqsptrctleagamtfhyii
eqgvcylvlceaafpkklafayledlhsefdeqhgkkvptvsrpysfiefdtfiqktkkl
yidsrarimvanieevl

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3egdD (D:)
qiytdiemnr

    Sequence, based on observed residues (ATOM records):
    >3egdD (D:)
tdiemnr