PDB entry 3efx

View 3efx on RCSB PDB site
Description: Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details
Class: toxin
Keywords: protein-carbohydrate complex, cholera toxin, heat-labile enterotoxin, blood group antigen
Deposited on 2008-09-10, released 2008-09-23
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.184
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxd1
  • Chain 'E':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxe_
  • Chain 'F':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxf_
  • Chain 'G':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxg_
  • Chain 'H':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxh_
  • Chain 'I':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxi_
  • Chain 'J':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxj_
  • Chain 'K':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxk_
  • Chain 'L':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxl_
  • Chain 'M':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOPe 2.04: d3efxm_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3efxD (D:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxD (D:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgqkkaie
rmkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3efxE (E:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxE (E:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpsqkkaie
rmkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3efxF (F:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxF (F:)
apqnitelcseyhntqiytindkilsyteslagkemaiitfkngatfqvevdsqkkaier
mkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >3efxG (G:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxG (G:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpqkkaier
mkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >3efxH (H:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxH (H:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpghidsqk
kaiermkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >3efxI (I:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxI (I:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpqkkaier
mkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >3efxJ (J:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxJ (J:)
apqnitelcseyhntqiytindkilsyteslagremaiitfkngatfqvevqkkaiermk
dtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >3efxK (K:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxK (K:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvekkaiermkd
tlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >3efxL (L:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxL (L:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpdsqkkai
ermkdtlriaylteakveklcvwnnktpnsiaaisma

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >3efxM (M:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman

    Sequence, based on observed residues (ATOM records): (download) 
    >3efxM (M:)
apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisma