PDB entry 3efx

View 3efx on RCSB PDB site
Description: Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details
Class: toxin
Keywords: protein-carbohydrate complex, cholera toxin, heat-labile enterotoxin, blood group antigen
Deposited on 2008-09-10, released 2008-09-23
The last revision prior to the SCOP 1.75 freeze date was dated 2008-10-07, with a file datestamp of 2008-10-03.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.184
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxd1
  • Chain 'E':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxe1
  • Chain 'F':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxf1
  • Chain 'G':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxg1
  • Chain 'H':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxh1
  • Chain 'I':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxi1
  • Chain 'J':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxj1
  • Chain 'K':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxk1
  • Chain 'L':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxl1
  • Chain 'M':
    Compound: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain
    Species: Vibrio cholerae, Escherichia coli [TaxId:37965]
    Database cross-references and differences (RAF-indexed):
    • PDB 3EFX (0-End)
    Domains in SCOP 1.75: d3efxm1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3efxD (D:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxD (D:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgqkkaie
    rmkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >3efxE (E:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxE (E:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpsqkkaie
    rmkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >3efxF (F:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxF (F:)
    apqnitelcseyhntqiytindkilsyteslagkemaiitfkngatfqvevdsqkkaier
    mkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >3efxG (G:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxG (G:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpqkkaier
    mkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >3efxH (H:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxH (H:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpghidsqk
    kaiermkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >3efxI (I:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxI (I:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpqkkaier
    mkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >3efxJ (J:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxJ (J:)
    apqnitelcseyhntqiytindkilsyteslagremaiitfkngatfqvevqkkaiermk
    dtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'K':
    Sequence, based on SEQRES records: (download)
    >3efxK (K:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxK (K:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvekkaiermkd
    tlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >3efxL (L:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxL (L:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpdsqkkai
    ermkdtlriaylteakveklcvwnnktpnsiaaisma
    

  • Chain 'M':
    Sequence, based on SEQRES records: (download)
    >3efxM (M:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisman
    

    Sequence, based on observed residues (ATOM records): (download)
    >3efxM (M:)
    apqnitelcseyhntqiytindkilsyteslagkremaiitfkngatfqvevpgsqhids
    qkkaiermkdtlriaylteakveklcvwnnktpnsiaaisma