PDB entry 3efh

View 3efh on RCSB PDB site
Description: Crystal structure of human phosphoribosyl pyrophosphate synthetase 1
Class: transferase
Keywords: TRANSFERASE, Charcot-Marie-Tooth disease, Deafness, Disease mutation, Gout, Kinase, Magnesium, Metal-binding, Nucleotide biosynthesis, Polymorphism
Deposited on 2008-09-08, released 2008-09-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.216
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ribose-phosphate pyrophosphokinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRPS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3efha1, d3efha2
  • Chain 'B':
    Compound: Ribose-phosphate pyrophosphokinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PRPS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3efhb1, d3efhb2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3efhA (A:)
mpnikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgc
geindnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvag
adhiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvts
iadrlnvdfalihkerkkanevdrmvlvgdvkdrvailvddmadtcgtichaadkllsag
atrvyailthgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeai
rrthngesvsylfshvpllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3efhA (A:)
nikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgcge
indnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvagad
hiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvtsia
drlnvdfalihkerkmvlvgdvkdrvailvddmadtcgtichaadkllsagatrvyailt
hgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeairrthngesv
sylfshv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3efhB (B:)
mpnikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgc
geindnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvag
adhiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvts
iadrlnvdfalihkerkkanevdrmvlvgdvkdrvailvddmadtcgtichaadkllsag
atrvyailthgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeai
rrthngesvsylfshvpllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3efhB (B:)
nikifsgsshqdlsqkiadrlglelgkvvtkkfsnqetcveigesvrgedvyivqsgcge
indnlmelliminackiasasrvtavipcfpyarqdkkdksrapisaklvanmlsvagad
hiitmdlhasqiqgffdipvdnlyaepavlkwirenisewrnctivspdaggakrvtsia
drlnvdfalihkerkmvlvgdvkdrvailvddmadtcgtichaadkllsagatrvyailt
hgifsgpaisrinnacfeavvvtntipqedkmkhcskiqvidismilaeairrthngesv
sylfshv