PDB entry 3ee5

View 3ee5 on RCSB PDB site
Description: Crystal structure of human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4GAL-T1) in complex with GLCNAC-Beta1,3-Gal-Beta-Naphthalenemethanol
Class: transferase
Keywords: Closed conformation, carbohydrate acceptor binding, Alternative initiation, Cell membrane, Congenital disorder of glycosylation, Glycoprotein, Glycosyltransferase, Golgi apparatus, Manganese, Membrane, Metal-binding, Secreted, Signal-anchor, Transferase, Transmembrane
Deposited on 2008-09-04, released 2009-01-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.206
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • engineered (225-226)
      • engineered (228)
    Domains in SCOPe 2.07: d3ee5a_
  • Chain 'B':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • engineered (225-226)
      • engineered (228)
    Domains in SCOPe 2.07: d3ee5b_
  • Chain 'C':
    Compound: Beta-1,4-galactosyltransferase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: B4GALT1, GGTB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15291 (14-286)
      • engineered (225-226)
      • engineered (228)
    Domains in SCOPe 2.07: d3ee5c_
  • Heterogens: UDH, 2NA, SO4, MN, GOL, DIO, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ee5A (A:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >3ee5A (A:)
slpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvaiiipfr
nrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdydytcfv
fsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqfltingfpn
nywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknepnpqrfdriahtket
mlsdglnsltyqvldvqryplytqitvdigtps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ee5B (B:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >3ee5B (B:)
slpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvaiiipfr
nrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdydytcfv
fsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqfltingfpn
nywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknepnpqrfdriahtket
mlsdglnsltyqvldvqryplytqitvdigtps

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3ee5C (C:)
asmtggqqmgrgsaslpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprd
cvsphkvaiiipfrnrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvg
fqealkdydytcfvfsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsa
lskqqfltingfpnnywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknep
npqrfdriahtketmlsdglnsltyqvldvqryplytqitvdigtps

    Sequence, based on observed residues (ATOM records): (download) 
    >3ee5C (C:)
slpacpeespllvgpmliefnmpvdlelvakqnpnvkmggryaprdcvsphkvaiiipfr
nrqehlkywlyylhpvlqrqqldygiyvinqagdtifnrakllnvgfqealkdydytcfv
fsdvdlipmndhnayrcfsqprhisvamdkfgfslpyvqyfggvsalskqqfltingfpn
nywgwggedddifnrlvfrgmsisrpnavvgttrhirhsrdkknepnpqrfdriahtket
mlsdglnsltyqvldvqryplytqitvdigtps