PDB entry 3edr

View 3edr on RCSB PDB site
Description: The crystal structure of caspase-7 in complex with Acetyl-LDESD-CHO
Deposited on 2008-09-03, released 2008-10-28
The last revision was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.201
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase-7
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: caspase-7
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: caspase-7
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: caspase-7
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP7, MCH3
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Inhibitor Ac-ldesd-cho peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EDR
  • Chain 'F':
    Compound: Inhibitor Ac-ldesd-cho peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EDR (Start-4)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3edrA (A:)
akpdrssfvpslfskkkknvtmrsikttrdrvptyqynmnfeklgkciiinnknfdkvtg
mgvrngtdkdaealfkcfrslgfdvivyndcscakmqdllkkaseedhtnaacfacills
hgeenviygkdgvtpikdltahfrgdrcktllekpklffiqacrgtelddgiq

    Sequence, based on observed residues (ATOM records):
    >3edrA (A:)
yqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsca
kmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktllek
pklffiqacrgtelddgiq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3edrB (B:)
anprykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvn
drvarhfesqsddphfhekkqipcvvsmltkelyfsq

    Sequence, based on observed residues (ATOM records):
    >3edrB (B:)
ykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvndrva
rhfesqsddphfhekkqipcvvsmltkelyfsq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3edrC (C:)
akpdrssfvpslfskkkknvtmrsikttrdrvptyqynmnfeklgkciiinnknfdkvtg
mgvrngtdkdaealfkcfrslgfdvivyndcscakmqdllkkaseedhtnaacfacills
hgeenviygkdgvtpikdltahfrgdrcktllekpklffiqacrgtelddgiq

    Sequence, based on observed residues (ATOM records):
    >3edrC (C:)
rdrvptyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivy
ndcscakmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrc
ktllekpklffiqacrgtelddgiq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3edrD (D:)
anprykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvn
drvarhfesqsddphfhekkqipcvvsmltkelyfsq

    Sequence, based on observed residues (ATOM records):
    >3edrD (D:)
ykipveadflfaystvpgyyswrspgrgswfvqalcsileehgkdleimqiltrvndrva
rhfesqsddphfhekkqipcvvsmltkelyfsq

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >3edrE (E:)
ldesx

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >3edrF (F:)
ldesx