PDB entry 3edq

View 3edq on RCSB PDB site
Description: crystal structure of caspase-3 with inhibitor ac-ldesd-cho
Deposited on 2008-09-03, released 2008-10-28
The last revision was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 1.61 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP3, CPP32
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP3, CPP32
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42574 (Start-101)
      • expression tag (102)
  • Chain 'C':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP3, CPP32
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Caspase-3
    Species: Homo sapiens [TaxId:9606]
    Gene: CASP3, CPP32
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42574 (Start-101)
      • expression tag (102)
  • Chain 'E':
    Compound: AC-LDESD-CHO peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EDQ (0-4)
  • Chain 'F':
    Compound: AC-LDESD-CHO peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 3EDQ (0-4)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >3edqA (A:)
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietd

    Sequence, based on observed residues (ATOM records):
    >3edqA (A:)
nsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltre
eivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltgk
pklfiiqacrgteldcgiet

  • Chain 'B':
    Sequence, based on SEQRES records:
    >3edqB (B:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3edqB (B:)
kipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhiltrvnrkvat
efesfsfdatfhakkqipcivsmltkelyfyhh

  • Chain 'C':
    Sequence, based on SEQRES records:
    >3edqC (C:)
sgisldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnk
ndltreeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrc
rsltgkpklfiiqacrgteldcgietd

    Sequence, based on observed residues (ATOM records):
    >3edqC (C:)
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgiet

  • Chain 'D':
    Sequence, based on SEQRES records:
    >3edqD (D:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >3edqD (D:)
kipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhiltrvnrkvat
efesfsfdatfhakkqipcivsmltkelyfyhh

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >3edqE (E:)
ldesd

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >3edqF (F:)
ldesd