PDB entry 3eaz

View 3eaz on RCSB PDB site
Description: Crystal structure of SH2 domain of Human Csk (carboxyl-terminal src kinase), C122S mutant.
Class: transferase
Keywords: SH2, CSK, DISULFIDE, OXIDIZED Reduced, ATP-binding, Cell membrane, Cytoplasm, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase
Deposited on 2008-08-26, released 2009-11-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-11-10, with a file datestamp of 2009-11-06.
Experiment type: XRAY
Resolution: 1.31 Å
R-factor: 0.196
AEROSPACI score: 0.71 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Tyrosine-protein kinase CSK
  Species: Homo sapiens [TaxId:9606]
  Gene: CSK
  Database cross-references and differences (RAF-indexed):
  • Uniprot P41240 (0-End)
    • engineered (49)
  Domains in SCOPe 2.05: d3eaza_
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >3eazA (A:)
  agtklslmpwfhgkitreqaerllyppetglflvrestnypgdytlcvssdgkvehyrim
  yhasklsideevyfenlmqlvehytsdadglctrlikpkvmegtva
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3eazA (A:)
  agtklslmpwfhgkitreqaerllyppetglflvrestnypgdytlcvssdgkvehyrim
  yhasklsideevyfenlmqlvehytsdadglctrlikpkvme