PDB entry 3e7s

View 3e7s on RCSB PDB site
Description: Structure of bovine eNOS oxygenase domain with inhibitor AR-C95791
Class: oxidoreductase
Keywords: NITRIC OXIDE SYNTHASE, NOS, HEME, TETRAHYDROBIOPTERIN, OXIDOREDUCTASE Calmodulin-binding, FAD, FMN, Iron, Metal-binding, NADP, Oxidoreductase, Polymorphism, Zinc
Deposited on 2008-08-18, released 2008-10-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-06-09, with a file datestamp of 2009-06-05.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.212
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase, endothelial
    Species: Bos taurus [TaxId:9913]
    Gene: NOS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29473
      • see remark 999 (43)
    Domains in SCOPe 2.07: d3e7sa_
  • Chain 'B':
    Compound: Nitric oxide synthase, endothelial
    Species: Bos taurus [TaxId:9913]
    Gene: NOS3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29473
      • see remark 999 (43)
    Domains in SCOPe 2.07: d3e7sb_
  • Heterogens: ZN, HEC, AT2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3e7sA (A:)
nsptltrppegpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprklqtrps
pgpppaeqllsqardfinqyyssikrsgsqaheerlqeveaevastgtyhlreselvfga
kqawrnaprcvgriqwgklqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqr
apgrgdfriwnsqlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllq
apdeapelfvlppelvlevplehptlewfaalglrwyalpavsnmlleigglefsaapfs
gwymsteigtrnlcdphryniledvavcmdldtrttsslwkdkaaveinlavlhsfqlak
vtivdhhaatvsfmkhldneqkarggcpadwawivppisgsltpvfhqemvnyilspafr
yqpdpwkgsat

    Sequence, based on observed residues (ATOM records): (download) 
    >3e7sA (A:)
rppegpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprkeqllsqardfin
qyyssikrsgsqaheerlevastgtyhlreselvfgakqawrnaprcvgriqwgklqvfd
ardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriwnsqlvryagyrqq
dgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfvlppelvlevpleh
ptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigtrnlcdphrynile
dvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaatvsfmkhldneqka
rggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3e7sB (B:)
nsptltrppegpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprklqtrps
pgpppaeqllsqardfinqyyssikrsgsqaheerlqeveaevastgtyhlreselvfga
kqawrnaprcvgriqwgklqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqr
apgrgdfriwnsqlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllq
apdeapelfvlppelvlevplehptlewfaalglrwyalpavsnmlleigglefsaapfs
gwymsteigtrnlcdphryniledvavcmdldtrttsslwkdkaaveinlavlhsfqlak
vtivdhhaatvsfmkhldneqkarggcpadwawivppisgsltpvfhqemvnyilspafr
yqpdpwkgsat

    Sequence, based on observed residues (ATOM records): (download) 
    >3e7sB (B:)
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprklppaeqllsqardfin
qyyssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprcvgriqwgk
lqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriwnsqlvrya
gyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfvlppelvle
vplehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigtrnlcdphr
yniledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaatvsfmkhld
neqkarggcpadwawivppisgsltpvfhqemvnyilspafryqpdpwk